BRAFV600E Mutation Status of Involuting and Stable Nevi in Dabrafenib Therapy with or without Trametinib

McClenahan, Phil, Lin, Lynlee L., Tan, Jean-Marie, Flewell-Smith, Ross, Schaider, Helmut, Jagirdar, Kasturee, Atkinson, Victoria, Lambie, Duncan, Prow, Tarl W., Sturm, Richard A. and Soyer, Peter (2014) BRAFV600E Mutation Status of Involuting and Stable Nevi in Dabrafenib Therapy with or without Trametinib. JAMA Dermatology, 150 10: 1079-1082. doi:10.1001/jamadermatol.2014.436

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
UQ330852_OA.pdf Full text (open access) application/pdf 311.88KB 0

Author McClenahan, Phil
Lin, Lynlee L.
Tan, Jean-Marie
Flewell-Smith, Ross
Schaider, Helmut
Jagirdar, Kasturee
Atkinson, Victoria
Lambie, Duncan
Prow, Tarl W.
Sturm, Richard A.
Soyer, Peter
Title BRAFV600E Mutation Status of Involuting and Stable Nevi in Dabrafenib Therapy with or without Trametinib
Journal name JAMA Dermatology   Check publisher's open access policy
ISSN 2168-6068
2168-6084
Publication date 2014-04-02
Year available 2014
Sub-type Article (original research)
DOI 10.1001/jamadermatol.2014.436
Open Access Status File (Publisher version)
Volume 150
Issue 10
Start page 1079
End page 1082
Total pages 4
Place of publication Chicago, IL, United States
Publisher American Medical Association
Language eng
Abstract IMPORTANCE Recent advances in targeting BRAF(V600E) mutations, which occur in roughly 50% of melanomas and 70% of benign nevi, have improved response rates and survival in patients with melanoma. With increased survival, the importance of other comorbidities increases and requires consideration in long-term management. This case report discusses dynamic dermoscopic nevus changes that occur during dabrafenib therapy and offers some conclusions regarding BRAF mutations and the changes.
Keyword Dermatology
Dermatology
Q-Index Code CX
Q-Index Status Confirmed Code
Grant ID APP1004999
Institutional Status UQ

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 10 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 12 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 22 May 2014, 20:50:35 EST by Susan Allen on behalf of Institute for Molecular Bioscience