Experimental Trypanosoma evansi infection in the goat. I. Clinical signs and clinical pathology

Dargantes A.P., Reid S.A. and Copeman D.B. (2005) Experimental Trypanosoma evansi infection in the goat. I. Clinical signs and clinical pathology. Journal of Comparative Pathology, 133 4: 261-266. doi:10.1016/j.jcpa.2005.06.001


Author Dargantes A.P.
Reid S.A.
Copeman D.B.
Title Experimental Trypanosoma evansi infection in the goat. I. Clinical signs and clinical pathology
Journal name Journal of Comparative Pathology   Check publisher's open access policy
ISSN 0021-9975
Publication date 2005-01-01
Year available 2005
Sub-type Article (original research)
DOI 10.1016/j.jcpa.2005.06.001
Volume 133
Issue 4
Start page 261
End page 266
Total pages 6
Publisher ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
Language eng
Subject 1103 Clinical Sciences
Abstract A strain of Trypanosoma evansi isolated from an equine case of surra in Mindanao, Philippines was used to infect intravenously two groups (A and B) of five male goats aged 8-10 months. Animals of groups A and B received 5000 and 50 000 trypanosomes, respectively, and five further animals (group C) served as uninfected controls. Four of the 10 infected goats died 8-78 days after inoculation. Group C goats gained weight (mean 22.8 g/day) while infected goats in groups A and B lost weight (means of 21.4 and 45.0 g/day, respectively). Parasitaemia fluctuated regularly between peaks and troughs, with repeated periods of about 6 days during which no trypanosomes were detected in the blood. Clinical signs and clinico-pathological changes in infected goats were not pathognomonic in the absence of parasites in the blood, and leucocytosis was not a reliable indicator of infection. It was concluded that in endemic areas fluctuating fever, progressive emaciation, anaemia, coughing, testicular enlargement and diarrhoea are suggestive of surra; confirmation, however, may necessitate examination of blood every few days for trypanosomes, and possibly other diagnostic tests.
Keyword Goat
Parasitic infection
Surra
Trypanosoma evansi
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 10 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 13 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 20 May 2014, 21:00:59 EST by System User