The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus)

McInnes, L. M., Gillett, A., Hanger, J., Reid, S. A. and Ryan, U. M. (2011) The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus). Parasitology, 138 7: 873-883. doi:10.1017/S0031182011000369


Author McInnes, L. M.
Gillett, A.
Hanger, J.
Reid, S. A.
Ryan, U. M.
Title The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus)
Formatted title
The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus)
Journal name Parasitology   Check publisher's open access policy
ISSN 0031-1820
1469-8161
Publication date 2011-01-01
Sub-type Article (original research)
DOI 10.1017/S0031182011000369
Volume 138
Issue 7
Start page 873
End page 883
Total pages 11
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Language eng
Abstract Whole blood collected from koalas admitted to the Australian Zoo Wildlife Hospital (AZWH), Beerwah, QLd, Australia, during late 2006-2009 was tested using trypanosome species-specific 18S rDNA PCRs designed to amplify DNA from Trypanosoma irwini, T. gilletti and T. copemani. Clinical records for each koala sampled were reviewed and age, sex, blood packed cell volume (PCV), body condition, signs of illness, blood loss, trauma, chlamydiosis, bone marrow disease, koala AIDS and hospital admission outcome ('survival' / 'non-survival') were correlated with PCR results. Overall 73·8% (439/595) of the koalas were infected with at least 1 species of trypanosome. Trypanosoma irwini was detected in 423/595 (71·1%), T. gilletti in 128/595 (21·5%) and T. copemani in 26/595 (4·4%) of koalas. Mixed infections were detected in 125/595 (21%) with co-infections of T. irwini and T. gilletti (101/595, 17%) being most common. There was a statistical association between infection with T. gilletti with lower PCV values and body condition scores in koalas with signs of chlamydiosis, bone marrow disease or koala AIDS. No association between T. gilletti infection and any indicator of health was observed in koalas without signs of concurrent disease. This raises the possibility that T. gilletti may be potentiating other disease syndromes affecting koalas.
Keyword 18S rDNA
Koala
Pathogenicity
Potentiation
Trypanosoma
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 14 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 20 May 2014, 20:59:08 EST by System User on behalf of School of Public Health