Antimicrobial stewardship of β-lactams in intensive care units

Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014) Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 5: 581-595. doi:10.1586/14787210.2014.902308

Author Cotta, Menino Osbert
Roberts, Jason A.
Tabah, Alexis
Lipman, Jeffrey
Vogelaers, Dirk
Blot, Stijn
Title Antimicrobial stewardship of β-lactams in intensive care units
Journal name Expert Review of Anti-Infective Therapy   Check publisher's open access policy
ISSN 1478-7210
Publication date 2014-01-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1586/14787210.2014.902308
Open Access Status Not yet assessed
Volume 12
Issue 5
Start page 581
End page 595
Total pages 15
Place of publication London, United Kingdom
Publisher Expert Reviews Ltd.
Language eng
Subject 2725 Infectious Diseases
2726 Microbiology (medical)
2404 Microbiology
2406 Virology
Abstract Stewardship of all antimicrobials, including β-lactam antibiotics, has gained in prominence over the last decade. Appropriate use of these agents has become vitally important; especially in the treatment and management of the critically ill. Opportunities therefore exist to develop innovations to optimise the use of antimicrobials in places like the intensive care unit. The next few years represent an important window in which routine antimicrobial stewardship principles such as surveillance of local ecology, minimising overlap of spectrum of activity and prompt de-escalation upon review of cultures can be integrated with new technologies including improved diagnostic techniques, individualised dosing strategies and computerised decision support. It is important though, that these measures to improve stewardship in the intensive care unit continue to be critically evaluated in the literature.
Keyword Antibiotics
Antimicrobial resistance
Critical care unit
Intensive care unit
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Official 2015 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
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