Multifunctional nanoworms and nanorods through a one-step aqueous dispersion polymerization

Jia, Zhongfan, Bobrin, Valentin A., Truong, Nghia P., Gillard, Marianne and Monteiro, Michael J. (2014) Multifunctional nanoworms and nanorods through a one-step aqueous dispersion polymerization. Journal of the American Chemical Society, 136 16: 5824-5827. doi:10.1021/ja500092m


Author Jia, Zhongfan
Bobrin, Valentin A.
Truong, Nghia P.
Gillard, Marianne
Monteiro, Michael J.
Title Multifunctional nanoworms and nanorods through a one-step aqueous dispersion polymerization
Journal name Journal of the American Chemical Society   Check publisher's open access policy
ISSN 0002-7863
1520-5126
Publication date 2014-04-23
Year available 2014
Sub-type Article (original research)
DOI 10.1021/ja500092m
Open Access Status DOI
Volume 136
Issue 16
Start page 5824
End page 5827
Total pages 4
Place of publication Washington, DC United States
Publisher American Chemical Society
Language eng
Subject 1600 Chemistry
1503 Business and Management
1303 Specialist Studies in Education
1505 Marketing
Abstract Producing synthetic soft worm and rod structures with multiple chemical functionalities on the surface would provide potential utility in drug delivery, nanoreactors, tissue engineering, diagnostics, rheology modifiers, enzyme mimics, and many other applications. Here, we have synthesized multifunctional worms and rods directly in water using a one-step reversible addition-fragmentation chain transfer (RAFT)-mediated dispersion polymerization at high weight fractions of polymer (>10 wt %). The chain-end functionalities included alkyne, pyridyl disulfide, dopamine, β-thiolactone, and biotin groups. These groups could further be converted or coupled with biomolecules or polymers. We further demonstrated a nanorod colorimetric system with good control over the attachment of fluorescent probes.
Keyword Chemistry, Multidisciplinary
Chemistry
CHEMISTRY, MULTIDISCIPLINARY
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Australian Institute for Bioengineering and Nanotechnology Publications
 
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