Immunosuppressive roles of natural killer T (NKT) cells in the skin

McKee, Sara J., Mattarollo, Stephen R. and Leggatt, Graham R. (2014) Immunosuppressive roles of natural killer T (NKT) cells in the skin. Journal of Leukocyte Biology, 96 1: 49-54. doi:10.1189/jlb.4RU0114-001R


Author McKee, Sara J.
Mattarollo, Stephen R.
Leggatt, Graham R.
Title Immunosuppressive roles of natural killer T (NKT) cells in the skin
Journal name Journal of Leukocyte Biology   Check publisher's open access policy
ISSN 0741-5400
1938-3673
Publication date 2014-07-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1189/jlb.4RU0114-001R
Open Access Status Not yet assessed
Volume 96
Issue 1
Start page 49
End page 54
Total pages 6
Place of publication Bethesda, MD, United States
Publisher Federation of American Societies for Experimental Biology
Language eng
Abstract The skin is a complex immunological niche providing immunity to invading pathogens while simultaneously maintaining tolerance to innocuous environmental antigens. Consistent with this complex response, the skin is resident to both immunosuppressive and effector cell populations whose activities are tightly regulated. While NKT cells can activate immune responses in the skin, this review will highlight studies on UV-induced photodamage, models of NMSCs, transplantation and allergic inflammation where NKT cells appear to have an immunosuppressive role in the skin.
Keyword Cell Biology
Hematology
Immunology
Cell Biology
Hematology
Immunology
CELL BIOLOGY
HEMATOLOGY
IMMUNOLOGY
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
UQ Diamantina Institute Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 20 May 2014, 07:17:23 EST by Dr Graham Leggatt on behalf of UQ Diamantina Institute