What causes canine sino-nasal aspergillosis? A molecular approach to species identification

Talbot, Jessica J., Johnson, Lynelle R., Martin, Patricia, Beatty, Julia A., Sutton, Deanna A., Billen, Frédéric, Halliday, Catriona L., Gibson, Justine S., Kidd, Sarah, Steiner, Jörg M., Ujvari, Beata and Barrs, Vanessa R. (2014) What causes canine sino-nasal aspergillosis? A molecular approach to species identification. Veterinary Journal, 200 1: 17-21. doi:10.1016/j.tvjl.2014.01.009

Author Talbot, Jessica J.
Johnson, Lynelle R.
Martin, Patricia
Beatty, Julia A.
Sutton, Deanna A.
Billen, Frédéric
Halliday, Catriona L.
Gibson, Justine S.
Kidd, Sarah
Steiner, Jörg M.
Ujvari, Beata
Barrs, Vanessa R.
Title What causes canine sino-nasal aspergillosis? A molecular approach to species identification
Journal name Veterinary Journal   Check publisher's open access policy
ISSN 1090-0233
Publication date 2014-04-01
Sub-type Article (original research)
DOI 10.1016/j.tvjl.2014.01.009
Volume 200
Issue 1
Start page 17
End page 21
Total pages 5
Place of publication London, United Kingdom
Publisher Elsevier
Language eng
Formatted abstract
On the basis of phenotypic identification methods, Aspergillus fumigatus is reported as the most commonly identified aetiological agent of canine sino-nasal aspergillosis (SNA). However, definitive identification of Aspergillus spp. using phenotypic features alone is unreliable. The aim of this study was to determine the molecular identities of fungal species causing SNA in dogs. Genomic DNA was extracted from 91 fungal isolates from 90 dogs diagnosed with SNA in Australia, the USA and Belgium, and the ITS1-5.8S-ITS2 ribosomal DNA and partial β-tubulin regions were sequenced. Eighty-eight of 91 (96.7%) isolates were identified as A. fumigatus and 3/91 (3.3%) belonged to Aspergillus section Nigri spp. (Aspergillus tubingensis: 2/91; Aspergillus uvarum: 1/91). These findings confirm that A. fumigatus is the most common aetiological agent of canine SNA. This is the first report to document a pathogenic role for A. tubingensis and A. uvarum in dogs. 
Keyword Sino-nasal aspergillosis
Aspergillus fumigatus
Aspergillus tubingensis
Aspergillus uvarum
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Veterinary Science Publications
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 15 May 2014, 00:10:00 EST by Ms Justine Gibson on behalf of School of Veterinary Science