Evolutionary origin of gastrulation: Insights from sponge development

Nakanishi, Nagayasu, Sogabe, Shunsuke and Degnan, Bernard M. (2014) Evolutionary origin of gastrulation: Insights from sponge development. BMC Biology, 12 26: . doi:10.1186/1741-7007-12-26


Author Nakanishi, Nagayasu
Sogabe, Shunsuke
Degnan, Bernard M.
Title Evolutionary origin of gastrulation: Insights from sponge development
Journal name BMC Biology   Check publisher's open access policy
ISSN 1741-7007
Publication date 2014-03-28
Year available 2014
Sub-type Article (original research)
DOI 10.1186/1741-7007-12-26
Open Access Status DOI
Volume 12
Issue 26
Total pages 9
Place of publication London, United Kingdom
Publisher BioMed Central
Language eng
Abstract Background: The evolutionary origin of gastrulation-defined as a morphogenetic event that leads to the establishment of germ layers-remains a vexing question. Central to this debate is the evolutionary relationship between the cell layers of sponges (poriferans) and eumetazoan germ layers. Despite considerable attention, it remains unclear whether sponge cell layers undergo progressive fate determination akin to eumetazoan primary germ layer formation during gastrulation.Results: Here we show by cell-labelling experiments in the demosponge Amphimedon queenslandica that the cell layers established during embryogenesis have no relationship to the cell layers of the juvenile. In addition, juvenile epithelial cells can transdifferentiate into a range of cell types and move between cell layers. Despite the apparent lack of cell layer and fate determination and stability in this sponge, the transcription factor GATA, a highly conserved eumetazoan endomesodermal marker, is expressed consistently in the inner layer of A. queenslandica larvae and juveniles.Conclusions: Our results are compatible with sponge cell layers not undergoing progressive fate determination and thus not being homologous to eumetazoan germ layers. Nonetheless, the expression of GATA in the sponge inner cell layer suggests a shared ancestry with the eumetazoan endomesoderm, and that the ancestral role of GATA in specifying internalised cells may antedate the origin of germ layers. Together, these results support germ layers and gastrulation evolving early in eumetazoan evolution from pre-existing developmental programs used for the simple patterning of cells in the first multicellular animals.
Keyword Evolution
Gastrulation
Germ layers
Sponge development
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Biological Sciences Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 21 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 24 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 11 May 2014, 10:05:37 EST by System User on behalf of School of Biological Sciences