Population variation in biomonitoring data for persistent organic pollutants (POPs): An examination of multiple population-based datasets for application to Australian pooled biomonitoring data

Aylward, Lesa L., Green, Evan, Porta, Miquel, Toms, Leisa-Maree, Den Hond, Elly, Schulz, Christine, Gasull, Magda, Pumarega, Jose, Conrad, Andre, Kolossa-Gehring, Marike, Schoeters, Greet and Mueller, Jochen F. (2014) Population variation in biomonitoring data for persistent organic pollutants (POPs): An examination of multiple population-based datasets for application to Australian pooled biomonitoring data. Environment International, 68 127-138. doi:10.1016/j.envint.2014.03.026


Author Aylward, Lesa L.
Green, Evan
Porta, Miquel
Toms, Leisa-Maree
Den Hond, Elly
Schulz, Christine
Gasull, Magda
Pumarega, Jose
Conrad, Andre
Kolossa-Gehring, Marike
Schoeters, Greet
Mueller, Jochen F.
Title Population variation in biomonitoring data for persistent organic pollutants (POPs): An examination of multiple population-based datasets for application to Australian pooled biomonitoring data
Journal name Environment International   Check publisher's open access policy
ISSN 0160-4120
1873-6750
Publication date 2014-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1016/j.envint.2014.03.026
Open Access Status Not yet assessed
Volume 68
Start page 127
End page 138
Total pages 12
Place of publication Kidlington, Oxford, United Kingdom
Publisher Pergamon
Language eng
Subject 2300 Environmental Science
Abstract Background: Australian national biomonitoring for persistent organic pollutants (POPs) relies upon age-specific pooled serum samples to characterize central tendencies of concentrations but does not provide estimates of upper bound concentrations. This analysis compares population variation from biomonitoring datasets from the US, Canada, Germany, Spain, and Belgium to identify and test patterns potentially useful for estimating population upper bound reference values for the Australian population. Methods: Arithmetic means and the ratio of the 95th percentile to the arithmetic mean (P95:mean) were assessed by survey for defined age subgroups for three polychlorinated biphenyls (PCBs 138, 153, and 180), hexachlorobenzene (HCB), p,p-dichlorodiphenyldichloroethylene (DDE), 2,2',4,4' tetrabrominated diphenylether (PBDE 47), perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). Results: Arithmetic mean concentrations of each analyte varied widely across surveys and age groups. However, P95:mean ratios differed to a limited extent, with no systematic variation across ages. The average P95:mean ratios were 2.2 for the three PCBs and HCB; 3.0 for DDE; 2.0 and 2.3 for PFOA and PFOS, respectively. The P95:mean ratio for PBDE 47 was more variable among age groups, ranging from 2.7 to 4.8. The average P95:mean ratios accurately estimated age group-specific P95s in the Flemish Environmental Health Survey II and were used to estimate the P95s for the Australian population by age group from the pooled biomonitoring data. Conclusions: Similar population variation patterns for POPs were observed across multiple surveys, even when absolute concentrations differed widely. These patterns can be used to estimate population upper bounds when only pooled sampling data are available.
Keyword Biomonitoring
Persistent organic pollutants
Population monitoring
Variation
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID FF 120100546
Institutional Status UQ

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 12 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 13 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 06 May 2014, 11:52:35 EST by System User on behalf of National Res Centre For Environmental Toxicology