Postexposure administration of halofantrine for the prevention of malaria

Shanks G.D., Edstein M.D., Kereu R.K., Spicer P.E. and Rieckmann K.H. (1993) Postexposure administration of halofantrine for the prevention of malaria. Clinical Infectious Diseases, 17 4: 628-631. doi:10.1093/clinids/17.4.628

Author Shanks G.D.
Edstein M.D.
Kereu R.K.
Spicer P.E.
Rieckmann K.H.
Title Postexposure administration of halofantrine for the prevention of malaria
Journal name Clinical Infectious Diseases   Check publisher's open access policy
ISSN 1058-4838
Publication date 1993-01-01
Year available 1993
Sub-type Article (original research)
DOI 10.1093/clinids/17.4.628
Volume 17
Issue 4
Start page 628
End page 631
Total pages 4
Place of publication CHICAGO
Language eng
Subject 2403 Immunology
Abstract Halofantrine was administered as prophylaxis for malaria to mine workers returning from endemic areas of Papua New Guinea. The men were randomly assigned to receive 500 mg of halofantrine daily for 3 days (n = 195) or 6 days (n = 150) or a total dose of 1,500 mg of chloroquine over 3 days (n = 55). None of the men receiving halofantrine developed falciparum malaria during the subsequent 28 days, whereas three men receiving chloroquine did develop this disease (P < .02). The administration of halofantrine after departure from an endemic area is one strategy for the prevention of falciparum malaria after short-term exposure.
Keyword Papua-New-Guinea
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 9 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 05 May 2014, 23:03:04 EST by Ms Kate Rowe on behalf of Scholarly Communication and Digitisation Service