Environmental contributions to childhood cancers

Norman, Rosana E., Ryan, Alexander, Grant, Kristen, Sitas, Freddy and Scott, James G. (2014) Environmental contributions to childhood cancers. Journal of Environmental Immunology and Toxicology, 2 2: 86-98. doi:10.7178/jeit.17

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Author Norman, Rosana E.
Ryan, Alexander
Grant, Kristen
Sitas, Freddy
Scott, James G.
Title Environmental contributions to childhood cancers
Journal name Journal of Environmental Immunology and Toxicology   Check publisher's open access policy
ISSN 2225-1219
Publication date 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.7178/jeit.17
Open Access Status DOI
Volume 2
Issue 2
Start page 86
End page 98
Total pages 13
Place of publication Philadelphia, PA, USA
Publisher STM Connect
Collection year 2015
Language eng
Abstract Recent increases in incidence of childhood cancers cannot be explained by genetic factors. Identifying the environmental risk factors that may explain increases in cancer incidence is an important step to reduce the overall burden of disease. The risk factors for which the most evidence exists include ionising radiation, ultraviolet radiation and chemicals such as benzene and pesticides, biological agents as well as parental smoking and parental substance use. Regarding the link between exposure to non-ionising radiation and development of cancer, the evidence was limited. Maternal vitamin supplementation may reduce the risk of cancer in offspring. Environmental exposures encountered during development and early childhood may be even more important contributors to the risk of cancer than exposures in adulthood and the early developmental period presents an important opportunity for cancer prevention.
Keyword Childhood cancers
Risk factors
Early life exposures
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

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Created: Tue, 29 Apr 2014, 12:29:38 EST by James Scott on behalf of Psychiatry - Royal Brisbane and Women's Hospital