Ventilation and cardiac related impedance changes in children undergoing corrective open heart surgery

Schibler, A., Pham, T.M.T., Moray, A.A. and Stocker, C. (2013) Ventilation and cardiac related impedance changes in children undergoing corrective open heart surgery. Physiological Measurement, 34 10: 1319-1327. doi:10.1088/0967-3334/34/10/1319

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Author Schibler, A.
Pham, T.M.T.
Moray, A.A.
Stocker, C.
Title Ventilation and cardiac related impedance changes in children undergoing corrective open heart surgery
Journal name Physiological Measurement   Check publisher's open access policy
ISSN 0967-3334
Publication date 2013-01-01
Sub-type Article (original research)
DOI 10.1088/0967-3334/34/10/1319
Open Access Status Not Open Access
Volume 34
Issue 10
Start page 1319
End page 1327
Total pages 9
Place of publication Bristol, England, U.K.
Publisher Institute of Physics Publishing Ltd.
Language eng
Subject 1304 Biophysics
1314 Physiology
2737 Physiology (medical)
Abstract Electrical impedance tomography (EIT) can determine ventilation and perfusion relationship. Most of the data obtained so far originates from experimental settings and in healthy subjects. The aim of this study was to demonstrate that EIT measures the perioperative changes in pulmonary blood flow after repair of a ventricular septum defect in children with haemodynamic relevant septal defects undergoing open heart surgery. In a 19 bed intensive care unit in a tertiary children's hospital ventilation and cardiac related impedance changes were measured using EIT before and after surgery in 18 spontaneously breathing patients. The EIT signals were either filtered for ventilation (ΔZV) or for cardiac (ΔZQ) related impedance changes. Impedance signals were then normalized (normΔZV, normΔZQ) for calculation of the global and regional impedance related ventilation perfusion relationship (normΔZV/normΔZQ). We observed a trend towards increased normΔZV in all lung regions, a significantly decreased normΔZQ in the global and anterior, but not the posterior lung region. The normΔZV/normΔZQ was significantly increased in the global and anterior lung region. Our study qualitatively validates our previously published modified EIT filtration technique in the clinical setting of young children with significant left-to-right shunt undergoing corrective open heart surgery, where perioperative assessment of the ventilation perfusion relation is of high clinical relevance.
Keyword EIT
electrical impedance tomography
open heart surgery
ventilation perfusion relationship
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 28 Apr 2014, 09:16:22 EST by Matthew Lamb on behalf of School of Medicine