Improving sexual health in men with prostate cancer: randomised controlled trial of exercise and psychosexual therapies

Cormie, Prue, Chambers, Suzanne K., Newton, Robert U., Gardiner, Robert A., Spry, Nigel, Taaffe, Dennis R., Joseph, David, Hamid, M. Akhlil, Chong, Peter, Hughes, David, Hamilton, Kyra and Galvao, Daniel A. (2014) Improving sexual health in men with prostate cancer: randomised controlled trial of exercise and psychosexual therapies. Bmc Cancer, 14 1: . doi:10.1186/1471-2407-14-199


Author Cormie, Prue
Chambers, Suzanne K.
Newton, Robert U.
Gardiner, Robert A.
Spry, Nigel
Taaffe, Dennis R.
Joseph, David
Hamid, M. Akhlil
Chong, Peter
Hughes, David
Hamilton, Kyra
Galvao, Daniel A.
Title Improving sexual health in men with prostate cancer: randomised controlled trial of exercise and psychosexual therapies
Journal name Bmc Cancer   Check publisher's open access policy
ISSN 1471-2407
Publication date 2014-03-01
Year available 2014
Sub-type Article (original research)
DOI 10.1186/1471-2407-14-199
Open Access Status DOI
Volume 14
Issue 1
Total pages 9
Place of publication London, United Kingdom
Publisher BioMed Central Ltd.
Language eng
Formatted abstract
 Background
Despite being a critical survivorship care issue, there is a clear gap in current knowledge of the optimal treatment of sexual dysfunction in men with prostate cancer. There is sound theoretical rationale and emerging evidence that exercise may be an innovative therapy to counteract sexual dysfunction in men with prostate cancer. Furthermore, despite the multidimensional aetiology of sexual dysfunction, there is a paucity of research investigating the efficacy of integrated treatment models. Therefore, the purpose of this study is to: 1) examine the efficacy of exercise as a therapy to aid in the management of sexual dysfunction in men with prostate cancer; 2) determine if combining exercise and brief psychosexual intervention results in more pronounced improvements in sexual health; and 3) assess if any benefit of exercise and psychosexual intervention on sexual dysfunction is sustained long term.

Methods/Design
A three-arm, multi-site randomised controlled trial involving 240 prostate cancer survivors will be implemented. Participants will be randomised to: 1) ‘Exercise’ intervention; 2) ‘Exercise + Psychosexual’ intervention; or 3) ‘Usual Care’. The Exercise group will receive a 6-month, group based, supervised resistance and aerobic exercise intervention. The Exercise + Psychosexual group will receive the same exercise intervention plus a brief psychosexual self-management intervention that addresses psychological and sexual well-being. The Usual Care group will maintain standard care for 6 months. Measurements for primary and secondary endpoints will take place at baseline, 6 months (post-intervention) and 1 year follow-up. The primary endpoint is sexual health and secondary endpoints include key factors associated with sexual health in men with prostate cancer.

Discussion
Sexual dysfunction is one of the most prevalent and distressing consequences of prostate cancer. Despite this, very little is known about the management of sexual dysfunction and current health care services do not adequately meet sexual health needs of survivors. This project will examine the potential role of exercise in the management of sexual dysfunction and evaluate a potential best-practice management approach by integrating pharmacological, physiological and psychological treatment modalities to address the complex and multifaceted aetiology of sexual dysfunction following cancer.
Keyword Prostate cancer
Sexual health
Erectile dysfunction
Exercise
Resistance training
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2015 Collection
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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