Polysubstance use: diagnostic challenges, patterns of use and health

Connor, Jason P., Gullo, Matthew J., White, Angela and Kelly, Adrian B. (2014) Polysubstance use: diagnostic challenges, patterns of use and health. Current Opinion in Psychiatry, 27 4: 269-275. doi:10.1097/YCO.0000000000000069

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Author Connor, Jason P.
Gullo, Matthew J.
White, Angela
Kelly, Adrian B.
Title Polysubstance use: diagnostic challenges, patterns of use and health
Journal name Current Opinion in Psychiatry   Check publisher's open access policy
ISSN 0951-7367
Publication date 2014-07-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/YCO.0000000000000069
Open Access Status File (Author Post-print)
Volume 27
Issue 4
Start page 269
End page 275
Total pages 7
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Abstract Purpose of review
Formatted abstract
Purpose of Review: Polysubstance use is common, particularly among some age groups and sub-cultures. It is also associated with elevated risk of psychiatric and physical health problems. We review recent research findings, comment on changes to polysubstance diagnoses, report on contemporary clinical and epidemiological polysubstance trends, and examine the efficacy of preventive and treatment approaches.

Recent Findings: Approaches to describing polysubstance use profiles are becoming more sophisticated. Models over the past 18 months that employ Latent Class Analysis typically report a no use or limited range cluster (alcohol/tobacco/marijuana), a moderate range cluster (limited range, plus amphetamine derivatives) and an extended range cluster (moderate range, plus nonmedical use of prescription drugs and other illicit drugs). Prevalence rates vary as a function of the population surveyed. Wider-ranging polysubstance users carry higher risk of comorbid psychopathology, health problems and deficits in cognitive functioning.

Summary: Wide-ranging polysubstance use is more prevalent in sub-cultures such as ‘ravers’ (dance club attendees), and those already dependent on substances. Health risks are elevated in these groups. Research into prevention and treatment of polysubstance use is underdeveloped. There may be benefit in targeting specific polysubstance use and/or risk profiles in prevention and clinical research.
Keyword Polysubstance
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID 1031909
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Faculty of Health and Behavioural Sciences -- Publications
Official 2015 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 45 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 54 times in Scopus Article | Citations
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Created: Sat, 26 Apr 2014, 03:12:01 EST by Matthew Gullo on behalf of Centre for Youth Substance Abuse