Yield enhancement in whispering gallery mode biosensors: Microfluidics and optical forces

Khosla, Kiran, Swaim, Jon D., Knittel, Joachim and Bowen, Warwick P. (2014) Yield enhancement in whispering gallery mode biosensors: Microfluidics and optical forces. Journal of Modern Optics, 61 5: 415-418. doi:10.1080/09500340.2014.890253


Author Khosla, Kiran
Swaim, Jon D.
Knittel, Joachim
Bowen, Warwick P.
Title Yield enhancement in whispering gallery mode biosensors: Microfluidics and optical forces
Journal name Journal of Modern Optics   Check publisher's open access policy
ISSN 0950-0340
1362-3044
Publication date 2014-03-12
Year available 2014
Sub-type Article (original research)
DOI 10.1080/09500340.2014.890253
Open Access Status DOI
Volume 61
Issue 5
Start page 415
End page 418
Total pages 4
Place of publication Abingdon, Oxfordshire, United Kingdom
Publisher Taylor and Francis Ltd.
Language eng
Subject 3107 Atomic and Molecular Physics, and Optics
Abstract We analyze the transport of 25 nm polystyrene nanoparticles through a microfluidic geometry housing a microtoroidal whispering gallery mode (WGM) sensor, taking into account diffusion, convection and optical forces. In particular, we look at the effects of tightly confining the flow of nanoparticles near the microtoroids equatorial rim, and calculate the average nanoparticle detection time as well as the total yield for passage of a 1 L sample. Compared to purely diffusive transport, flow rates on the order of 2 nL min give yield enhancements of up to 15, with nanoparticles being detected every 12 s. Even shorter detection times (1.2 s) can be achieved, but at the expense of lower yield. The sensors transport properties are further improved due to gradient optical forces exerted on the nanoparticles.
Keyword Detection
Microfluidics
Nanoparticle
Sensing
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
Official 2015 Collection
 
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