Stability of chitosan/montmorillonite nanohybrid towards enzymatic degradation on grafting with poly(lactic acid)

Depan, D., Kumar, A. Pratheep, Singh, R. P. and Misra, R. D. K. (2014) Stability of chitosan/montmorillonite nanohybrid towards enzymatic degradation on grafting with poly(lactic acid). Materials Science and Technology (United Kingdom), 30 5: 587-592. doi:10.1179/1743284713Y.0000000501


Author Depan, D.
Kumar, A. Pratheep
Singh, R. P.
Misra, R. D. K.
Title Stability of chitosan/montmorillonite nanohybrid towards enzymatic degradation on grafting with poly(lactic acid)
Journal name Materials Science and Technology (United Kingdom)   Check publisher's open access policy
ISSN 0267-0836
1743-2847
Publication date 2014-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1179/1743284713Y.0000000501
Open Access Status
Volume 30
Issue 5
Start page 587
End page 592
Total pages 6
Place of publication Leeds, W Yorks, United Kingdom
Publisher Maney Publishing
Language eng
Subject 2500 Materials Science
3104 Condensed Matter Physics
2210 Mechanical Engineering
2211 Mechanics of Materials
Abstract Enzymatic degradation of nanohybrid based on intercalation of chitosan (CS) within the galleries of montmorillonite (MMT) clay and grafted with poly(lactic acid) (PLA) was studied using esterase enzyme in phosphate buffered solution. Chitosan was first intercalated between the galleries of natural unmodified sodium MMT clay and subsequently grafted with PLA to prepare nanohybrids of CS-g-PLA/MMT. The prepared membranes were characterised by X-ray diffraction, transmission electron microscopy and NMR spectroscopy. The specimens were then subjected to enzymatic degradation to understand the effect of copolymerisation with PLA and the effect of incorporation of MMT in the CS matrix. The presence of MMT clay provided stability towards degradation of polymer matrix because of nanoscale dispersibility, thereby acting as a barrier towards the permeation of water molecules to induce hydrolysis of PLA. Similarly, the grafting of CS with crystalline PLA stabilised the CS matrix towards degradation, rendering it suitable for tissue engineering applications.
Keyword Chitosan
Degradation
Hydrolysis
Montmorillonite
Nanocomposite
Polylactide
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Australian Institute for Bioengineering and Nanotechnology Publications
 
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