Osteosarcoma treatment: state of the art

Ta, Hang T., Dass, Crispin R., Choong, Peter F. M. and Dunstan, Dave E. (2009) Osteosarcoma treatment: state of the art. Cancer and Metastasis Reviews, 28 1-2: 247-263. doi:10.1007/s10555-009-9186-7


Author Ta, Hang T.
Dass, Crispin R.
Choong, Peter F. M.
Dunstan, Dave E.
Title Osteosarcoma treatment: state of the art
Journal name Cancer and Metastasis Reviews   Check publisher's open access policy
ISSN 0167-7659
1573-7233
Publication date 2009-01-01
Year available 2009
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s10555-009-9186-7
Open Access Status
Volume 28
Issue 1-2
Start page 247
End page 263
Total pages 17
Place of publication New York, NY, United States
Publisher Springer
Language eng
Subject 2730 Oncology
1306 Cancer Research
2700 Medicine
Abstract Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or young adults. It is the second highest cause of cancer-related death in these age groups, mainly due to development of often fatal metastasis, usually in the lungs. Survival for these patients is poor despite the aggressive use of surgery, chemotherapy, and/or radiotherapy. Thus, new effective drugs and other forms of therapy are needed. This article reviews the biology and the state of the art management of OS. New experimental drugs and potential therapies targeting molecular pathways of OS are also discussed.
Keyword Bone
Cancer
Chemotherapy
Osteosarcoma
Radiotherapy
Tumor
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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