Early efficacy and complications of releasable sutures for trabeculectomy in primary angle-closure glaucoma: a randomized clinical trial

Liang, Yuan B., Feng, Mei Y., Meng, Hai L., Fan, Su J., Wang, Xing, Xie, Li L., Yi, Peng, Tang, Xin, Wang, Ning L. and Thomas, Ravi (2014) Early efficacy and complications of releasable sutures for trabeculectomy in primary angle-closure glaucoma: a randomized clinical trial. Journal of Glaucoma, 23 3: 136-141. doi:10.1097/IJG.0b013e31826981c9


Author Liang, Yuan B.
Feng, Mei Y.
Meng, Hai L.
Fan, Su J.
Wang, Xing
Xie, Li L.
Yi, Peng
Tang, Xin
Wang, Ning L.
Thomas, Ravi
Title Early efficacy and complications of releasable sutures for trabeculectomy in primary angle-closure glaucoma: a randomized clinical trial
Journal name Journal of Glaucoma   Check publisher's open access policy
ISSN 1536-481X
1057-0829
Publication date 2014-03-01
Year available 2014
Sub-type Article (original research)
DOI 10.1097/IJG.0b013e31826981c9
Volume 23
Issue 3
Start page 136
End page 141
Total pages 6
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams and Wilkins
Language eng
Formatted abstract
Purpose: To compare the postoperative intraocular pressure (IOP) and incidence of early complications after trabeculectomy with releasable suture to standard trabeculectomy in Chinese patients with primary angle-closure glaucoma.

Patients and Methods: One hundred seventy-five patients diagnosed as primary angle-closure glaucoma with 6 clock-hours or more of peripheral anterior synechia were randomly allocated to 2 treatment groups: 87 underwent standard trabeculectomy (S group: 2 interrupted permanent sutures to the scleral flap) and 88 received trabeculectomy with 2 permanent and 2 releasable sutures (R group). The postoperative IOP and complications during the first 3 months after surgery were compared.

Results: One hundred seventy-one patients (97.7%) attended the 3-month visit. The IOP in the first week after trabeculectomy was significantly higher in the R group: day 1, 17.3±8.6 versus 12.7±6.0 mm Hg (P<0.001); day 3, 18.0±7.3 versus 12.9±6.3 mm Hg (P<0.001); day 7, 14.8±6.3 versus 12.0±4.9 mm Hg (P=0.001), but no difference was observed after the second week (P=0.659 to 0.753). The incidence of transient hypotony was higher in S group (20.4%) than the R group (9.1%) (P=0.046); hypotony recovered in 80.8% (21/26) within 1 week. There was no difference in the occurrence of shallow chamber, choroidal detachment, macular edema, additional surgery, or hyphema (P=0.56 to 1.0).

Conclusions: The technique of releasable sutures for trabeculectomy used in this study did not demonstrate significant advantages over standard trabeculectomy. Releasable sutures were associated with some decrease in visual acuity and increase in postoperative complaints.
Keyword Releasable sutures
Trabeculectomy
Primary angle-closure glaucoma
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
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