Common genetic variants explain the majority of the correlation between height and intelligence: The generation scotland study

Marioni, Riccardo E., Batty, G. David, Hayward, Caroline, Kerr, Shona M., Campbell, Archie, Hocking, Lynne J., Porteous, David J., Visscher, Peter M. and Deary, Ian J. (2014) Common genetic variants explain the majority of the correlation between height and intelligence: The generation scotland study. Behavior Genetics, 44 2: 91-96. doi:10.1007/s10519-014-9644-z


Author Marioni, Riccardo E.
Batty, G. David
Hayward, Caroline
Kerr, Shona M.
Campbell, Archie
Hocking, Lynne J.
Porteous, David J.
Visscher, Peter M.
Deary, Ian J.
Title Common genetic variants explain the majority of the correlation between height and intelligence: The generation scotland study
Journal name Behavior Genetics   Check publisher's open access policy
ISSN 1573-3297
0001-8244
Publication date 2014-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1007/s10519-014-9644-z
Open Access Status DOI
Volume 44
Issue 2
Start page 91
End page 96
Total pages 6
Place of publication New York, NY United States
Publisher Springer New York LLC
Language eng
Subject 1311 Genetics
2716 Genetics (clinical)
1105 Dentistry
Abstract Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.
Keyword Generation Scotland
Genetic correlation
Height
Intelligence
Molecular genetics
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2015 Collection
UQ Diamantina Institute Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 15 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 01 Apr 2014, 11:13:00 EST by System User on behalf of Queensland Brain Institute