Paracetamol (acetaminophen): a blessing or a hidden curse?

Whitehouse, M. W. and Butters, D. E. (2014) Paracetamol (acetaminophen): a blessing or a hidden curse?. Inflammopharmacology, 22 1: 63-65. doi:10.1007/s10787-013-0189-1


Author Whitehouse, M. W.
Butters, D. E.
Title Paracetamol (acetaminophen): a blessing or a hidden curse?
Journal name Inflammopharmacology   Check publisher's open access policy
ISSN 0925-4692
1568-5608
Publication date 2014-02-01
Year available 2013
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s10787-013-0189-1
Open Access Status
Volume 22
Issue 1
Start page 63
End page 65
Total pages 3
Place of publication Basel, Switzerland
Publisher Birkhaeuser Science
Language eng
Abstract This Journal has recently published a splendid review of all you need to know about paracetamol (Graham et al. 2013), an analgesic widely used in the long-term management of arthritis. It clearly presents the science and hard facts. This commentary, by contrast, discusses some aspects of the metapharmacology of paracetamol; particularly by asking questions of how we might extract more benefit and suffer less adverse reactions when using this analgesic in the context of non-transient inflammation. As both a drug and a toxin, paracetamol exemplifies how beneficial and/or deleterious responses may be conditioned by circumstances (disease stress, nutritional status, fasting, etc.).
Keyword Analgesics
Conditional pharmacology/toxicology
Gastrotoxicity
Hepatotoxicity
Sulphur nutrition
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2014 Collection
School of Medicine Publications
 
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