High rate of HIV resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy

Gupta, Ravindra K., Goodall, Ruth L., Ranopa, Michael, Kityo, Cissy, Munderi, Paula, Lyagoba, Fred, Mugarura, Lincoln, Gilks, Charles F., Kaleebu, Pontiano and Pillay, Deenan (2014) High rate of HIV resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy. Clinical Infectious Diseases, 58 7: 1023-1026. doi:10.1093/cid/cit933


Author Gupta, Ravindra K.
Goodall, Ruth L.
Ranopa, Michael
Kityo, Cissy
Munderi, Paula
Lyagoba, Fred
Mugarura, Lincoln
Gilks, Charles F.
Kaleebu, Pontiano
Pillay, Deenan
Title High rate of HIV resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy
Journal name Clinical Infectious Diseases   Check publisher's open access policy
ISSN 1058-4838
1537-6591
Publication date 2014-04-01
Year available 2013
Sub-type Article (original research)
DOI 10.1093/cid/cit933
Volume 58
Issue 7
Start page 1023
End page 1026
Total pages 4
Place of publication Cary, NC, United States
Publisher Oxford University Press
Language eng
Formatted abstract
In a randomized comparison of nevirapine or abacavir with zidovudine plus lamivudine, routine viral load monitoring was not performed, yet 27% of individuals with viral failure at week 48 experienced resuppression by week 96 without switching. This supports World Health Organization recommendations that suspected viral failure should trigger adherence counseling and repeat measurement before a treatment switch is considered.
Keyword HIV
Failure
Viral resuppression
Resistance
Africa
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes First published online: December 18, 2013

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Public Health Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 18 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 28 Mar 2014, 21:27:44 EST by Charles Gilks on behalf of School of Public Health