Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery

Popat, Amirali, Jambhrunkar, Siddharth, Zhang, Jun, Yang, Jie, Zhang, Honwei, Meka, Anand and Yu, Chengzhong (2014) Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery. Chemical Communications, 50 42: 5547-5550. doi:10.1039/C4CC00620H


Author Popat, Amirali
Jambhrunkar, Siddharth
Zhang, Jun
Yang, Jie
Zhang, Honwei
Meka, Anand
Yu, Chengzhong
Title Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery
Journal name Chemical Communications   Check publisher's open access policy
ISSN 1359-7345
1364-548X
Publication date 2014-02-17
Sub-type Article (original research)
DOI 10.1039/C4CC00620H
Open Access Status DOI
Volume 50
Issue 42
Start page 5547
End page 5550
Total pages 4
Place of publication Cambridge, United Kingdom
Publisher R S C Publications
Language eng
Formatted abstract
Novel mesoporous silica nanoparticles (MSNs) responsive to multiple biological stimuli (pH and enzymes) were prepared through conjugation with a structure modified soy protein isolate. The particles show an extremely high pro-drug (sulfasalazine) loading with programmable drug release in simulated gastrointestinal fluid.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Sat, 22 Mar 2014, 23:38:26 EST by Mr Amirali Popat on behalf of Aust Institute for Bioengineering & Nanotechnology