Processionary caterpillar setae and equine fetal loss: 2. Histopathology of the fetal-placental unit from experimentally exposed mares

Todhunter, K. T., Cawdell-Smith, A. J., Bryden, W. L., Perkins, N. R. and Begg, A. P. (2014) Processionary caterpillar setae and equine fetal loss: 2. Histopathology of the fetal-placental unit from experimentally exposed mares. Veterinary Pathology, 51 6: 1131-1142. doi:10.1177/0300985813516639


Author Todhunter, K. T.
Cawdell-Smith, A. J.
Bryden, W. L.
Perkins, N. R.
Begg, A. P.
Title Processionary caterpillar setae and equine fetal loss: 2. Histopathology of the fetal-placental unit from experimentally exposed mares
Journal name Veterinary Pathology   Check publisher's open access policy
ISSN 0300-9858
1544-2217
Publication date 2014-11-01
Year available 2014
Sub-type Article (original research)
DOI 10.1177/0300985813516639
Open Access Status Not Open Access
Volume 51
Issue 6
Start page 1131
End page 1142
Total pages 14
Place of publication Thousand Oaks, CA, United States
Publisher Sage Publications
Language eng
Subject 3400 Veterinary
Abstract Pregnant mares were experimentally exposed to whole caterpillar or exoskeleton of the Processionary caterpillar (Ochrogaster lunifer) via gavage. Tissues were collected from resulting abortions and near or full-term pregnancies consisting of 13 aborted fetuses, 3 fetuses from treated euthanized mares, membranes of 5 foals, and organs from 3 foals. Three control membranes and 1 control fetus and membranes were examined. Caterpillar setal fragments were present in the allantochorion of the 3 fetuses from the euthanized mares and 11 of 12 aborted fetuses (92%) embedded in the chorion (villi or stroma) or allantois (vasculature or stroma). Placental locations of fragments ranged from the cervical pole region to the body encompassing the umbilical insertion and pregnant horn. Numbers in each fetus ranged from 1 to 7 fragments. Setae were present in the allantochorion from 2 to 22 days after the initial treatment. Acute to chronic active inflammation was present in all aborted fetuses, all euthanized fetuses, and within at least 1 tissue level (chorion, allantois, umbilical cord, or amnion) of the membranes from full-term foals. Amnionitis, funisitis, and allantoitis were present in 95% of the examined membranes. Pneumonia was present in 95% of the specimens, and bacteria were present histologically in 90.5% of the specimens with or without accompanying inflammation. The rapid migration of setae within 2 days after mare exposure suggests that direct setal migration into the fetal membranes is a likely initiating factor for equine amnionitis and fetal loss (EAFL).
Keyword Mare
Abortion
Amnionitis
Funisitis
Caterpillar
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Agriculture and Food Sciences
Official 2015 Collection
 
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Created: Fri, 21 Mar 2014, 04:24:18 EST by Dr Judy Cawdell-smith on behalf of Qld Alliance for Agriculture and Food Innovation