Automated unwrapping of MR phase images applied to BOLD MR-venography at 3 tesla

Rauscher, Alexander, Barth, Markus, Reichenbach, Jürgen R., Stollberger, Rudolf and Moser, Ewald (2003) Automated unwrapping of MR phase images applied to BOLD MR-venography at 3 tesla. Journal of Magnetic Resonance Imaging, 18 2: 175-180. doi:10.1002/jmri.10346

Author Rauscher, Alexander
Barth, Markus
Reichenbach, Jürgen R.
Stollberger, Rudolf
Moser, Ewald
Title Automated unwrapping of MR phase images applied to BOLD MR-venography at 3 tesla
Journal name Journal of Magnetic Resonance Imaging   Check publisher's open access policy
ISSN 1053-1807
Publication date 2003-08-01
Year available 2003
Sub-type Article (original research)
DOI 10.1002/jmri.10346
Open Access Status Not Open Access
Volume 18
Issue 2
Start page 175
End page 180
Total pages 6
Place of publication Hoboken, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Purpose: To improve the diagnostic value of BOLD MR-Venography by removing artifacts related to phase wrapping, particularly in regions of large background susceptibilities at high magnetic field strengths.

Materials and Methods: High resolution, T2*-weighted, single echo images were acquired on a 3 T system (Medspec 30/80 Avance, Bruker Medical, Ettlingen, Germany) with a three-dimensional, first order velocity compensated gradient echo sequence using a quadrature transmit/receive birdcage head coil. Data of nine healthy subjects and 19 patients were evaluated (age range: 27 to 76 years). To achieve improved MR-venograms, a fully automated region-growing phase unwrapping algorithm and subsequent high pass filtering were applied to phase images prior to the computation of minimum intensity projections.

Results: Considerably improved visualization of venous structures in regions of large background susceptibility-induced field inhomogeneities is demonstrated in healthy subjects and patients with brain tumors.

Conclusion: BOLD MR venograms are improved compared to previous post-processing algorithms. It is now feasible to obtain high-resolution images also in inhomogeneous regions, which increases the clinical potential of BOLD MR-Venography.
Keyword BOLD
Magnetic resonance imaging
Phase-unwrapping, 3 Tesla
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
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