Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla

Nobauer-Huhmann, Iris Melanie, Ba-Ssalamah, Ahmed, Mlynarik, Vladimir, Barth, Markus, Schoggl, Alexander, Heimberger, Karl, Matula, Christian, Fog, Amura, Kaider, Alexandra and Trattnig, Siegfried (2002) Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla. Investigative Radiology, 37 3: 114-119. doi:10.1097/00004424-200203000-00003

Author Nobauer-Huhmann, Iris Melanie
Ba-Ssalamah, Ahmed
Mlynarik, Vladimir
Barth, Markus
Schoggl, Alexander
Heimberger, Karl
Matula, Christian
Fog, Amura
Kaider, Alexandra
Trattnig, Siegfried
Title Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla
Journal name Investigative Radiology   Check publisher's open access policy
ISSN 0020-9996
Publication date 2002-03-01
Year available 2002
Sub-type Article (original research)
DOI 10.1097/00004424-200203000-00003
Open Access Status Not yet assessed
Volume 37
Issue 3
Start page 114
End page 119
Total pages 6
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Formatted abstract
Rationale and Objectives: To compare the diagnostic efficacy of a standard dose of MRI contrast agent in the evaluation of primary brain tumors and metastases using a high-field 3 tesla MR unit versus a 1.5 tesla MR unit.

Methods: Sixteen patients with brain tumors were examined at both field strengths using identical axial T1-SE protocols pre- and postcontrast (0.1 mmol/kg gadolinium), and post-contrast coronal 3D GRE with magnetization preparation (MP-RAGE), which was adjusted separately for each field strength. Evaluation of the images was performed quantitatively and, in the case of T1-SE images, also by visual assessment.

Results: Tumor-to-brain-contrast after gadolinium administration using statistical evaluation of MP-RAGE scans was significantly higher at 3 tesla (97.5) than at 1.5 tesla (46.3). The same was true for T1-SE sequences (93.0 vs. 72.1). Signal enhancement of the lesions in T1-SE sequences was not significantly different between both field strengths.

Conclusions: Administration of a gadolinium contrast agent produces higher contrast between tumor and normal brain at 3 tesla than at 1.5 tesla.
Keyword 3 tesla MRI
Brain tumors
High field strength
MRI contrast agent
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
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