Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease

De Cruz, Peter, Prideaux, Lani, Wagner, Josef, Ng, Siew C., McSweeney, Chris, Kirkwood, Carl, Morrison, Mark and Kamm, Michael A. (2012) Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease. Inflammatory Bowel Diseases, 18 2: 372-390. doi:10.1002/ibd.21751


Author De Cruz, Peter
Prideaux, Lani
Wagner, Josef
Ng, Siew C.
McSweeney, Chris
Kirkwood, Carl
Morrison, Mark
Kamm, Michael A.
Title Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease
Journal name Inflammatory Bowel Diseases   Check publisher's open access policy
ISSN 1078-0998
1536-4844
Publication date 2012-02-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/ibd.21751
Open Access Status Not Open Access
Volume 18
Issue 2
Start page 372
End page 390
Total pages 19
Place of publication Philadelphia, United States
Publisher Lippincott Williams & Wilkins
Language eng
Subject 2715 Gastroenterology
2723 Immunology and Allergy
Abstract The enteric bacterial flora play a key role in maintaining health. Inflammatory bowel disease is associated with quantitative and qualitative alterations in the microbiota. Early characterization of the microbiota involved culture-dependent techniques. The advent of metagenomic techniques, however, allows for structural and functional characterization using culture-independent methods. Changes in diversity, together with quantitative alterations in specific bacterial species, have been identified. The functional significance of these changes, and their pathogenic role, remain to be elucidated. Copyright
Keyword Enteric bacterial flora
Inflammatory bowel disease
Metagenomic, microbiota
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: UQ Diamantina Institute Publications
 
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