Bidirectional association between weight change and depression in mid-aged women: a community-based longitudinal study

Singh, G., Jackson, C. A., Dobson, A. and Mishra, G. D. (2013) Bidirectional association between weight change and depression in mid-aged women: a community-based longitudinal study. International Journal of Obesity, 38 4: 591-596. doi:10.1038/ijo.2013.127


Author Singh, G.
Jackson, C. A.
Dobson, A.
Mishra, G. D.
Title Bidirectional association between weight change and depression in mid-aged women: a community-based longitudinal study
Journal name International Journal of Obesity   Check publisher's open access policy
ISSN 0307-0565
1476-5497
Publication date 2013-08-06
Year available 2014
Sub-type Article (original research)
DOI 10.1038/ijo.2013.127
Open Access Status Not yet assessed
Volume 38
Issue 4
Start page 591
End page 596
Total pages 6
Place of publication London, United Kingdom
Publisher Nature Publishing
Language eng
Abstract BACKGROUND: There is some evidence for a bidirectional association between obesity and depression. However, studies examining weight change and depression are scarce and report inconsistent findings.
Formatted abstract
Background: There is some evidence for a bidirectional association between obesity and depression. However, studies examining weight change and depression are scarce and report inconsistent findings.

Objective: The objective was to investigate the relationship between average annual percentage weight change and depression in mid-aged women. Design:This was a prospective cohort study.

Subjects: A total of 8246 women aged 45-50 years at baseline participating in the Australian Longitudinal Study on Women's Health were surveyed every 3 years over a 12-year period. Information on body mass index and depression was collected at each survey. We used regression models to investigate the effect of weight change predicting depression and vice versa, by calculating odds ratios (ORs) with 95% confidence intervals (CIs).

Results: Weight gain was associated with an increased risk of prevalence (OR 1.39, 95% CI 1.25-1.56) and incidence (OR 1.30, 95% CI 1.14-1.49) of depression. However, in time-lagged analyses, where weight change between the two preceding surveys was used to predict incidence of depression at the current survey, no statistically significant associations with depression were found. Compared with women without depression, women with prevalent and incident depression had an increased risk of weight gain (OR 1.29, 95% CI 1.19-1.40 and OR 1.20, 95% CI 1.05-1.38, respectively). When incidence of depression was lagged with respect to weight change between the two subsequent surveys, depression remained associated with an increased risk (OR 1.19, 95% CI 1.00-1.41) of gaining weight.

Conclusion: These findings suggest that depression may cause weight gain over the next 3 years, but that weight change (loss or gain) may not lead to depression. Further research at shorter intervals, perhaps 6 monthly or yearly is needed to ascertain whether weight change is an independent predictor of depression in the shorter term.
Keyword Endocrinology & Metabolism
Nutrition & Dietetics
Endocrinology & Metabolism
Nutrition & Dietetics
ENDOCRINOLOGY & METABOLISM
NUTRITION & DIETETICS
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID APP1000986
Institutional Status UQ
Additional Notes Online publication: 6 August 2013.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Public Health Publications
 
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Created: Sat, 08 Mar 2014, 01:33:07 EST by Caroline Jackson on behalf of School of Public Health