Targeting virulence not viability in the search for future antibacterials

Heras, Begona, Scanlon, Martin J. and Martin, Jennifer L. (2014) Targeting virulence not viability in the search for future antibacterials. British Journal of Clinical Pharmacology, 79 2: 208-215. doi:10.1111/bcp.12356

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Author Heras, Begona
Scanlon, Martin J.
Martin, Jennifer L.
Title Targeting virulence not viability in the search for future antibacterials
Journal name British Journal of Clinical Pharmacology   Check publisher's open access policy
ISSN 0306-5251
1365-2125
Publication date 2014-02-19
Sub-type Article (original research)
DOI 10.1111/bcp.12356
Open Access Status File (Author Post-print)
Volume 79
Issue 2
Start page 208
End page 215
Total pages 8
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell
Language eng
Abstract New antibacterials need new approaches to overcome the problem of rapid antibiotic resistance. Here we review the development of potential new antibacterial drugs that do not kill bacteria or inhibit their growth, but combat disease instead by targeting bacterial virulence.
Keyword Antivirulence
Antibacterial
Bacterial infection
Pilicide
Quorum sensing
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Institute for Molecular Bioscience - Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 17 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 17 times in Scopus Article | Citations
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Created: Thu, 06 Mar 2014, 01:54:19 EST by Susan Allen on behalf of Institute for Molecular Bioscience