Disparities in breast cancer stage at diagnosis in urban and rural adult women: a systematic review and meta-analysis

Nguyen-Pham, Sallyanne, Leung, Janni and McLaughlin, Deirdre (2014) Disparities in breast cancer stage at diagnosis in urban and rural adult women: a systematic review and meta-analysis. Annals of Epidemiology, 24 3: 228-235. doi:10.1016/j.annepidem.2013.12.002


Author Nguyen-Pham, Sallyanne
Leung, Janni
McLaughlin, Deirdre
Title Disparities in breast cancer stage at diagnosis in urban and rural adult women: a systematic review and meta-analysis
Journal name Annals of Epidemiology   Check publisher's open access policy
ISSN 1047-2797
1873-2585
Publication date 2014-01-01
Year available 2013
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.annepidem.2013.12.002
Open Access Status Not Open Access
Volume 24
Issue 3
Start page 228
End page 235
Total pages 8
Place of publication Philadelphia, PA, United States
Publisher Elsevier
Language eng
Formatted abstract
Purpose: Survival from breast cancer is dependent on stage at diagnosis and some evidence suggests that rural women are more likely than urban women to be diagnosed with advanced stage disease. This systematic review and meta-analysis compared the stage of breast cancer at diagnosis between women residing in urban and rural areas.

Methods: PubMed (1951-2012), EMBASE (1966-2012), CINAHL (1982-2012), RURAL (1966-2012), and Sociological abstracts (1952-2012) were systematically searched in November 2012 for relevant peer reviewed studies. Studies on adult women were included if they reported quantitative comparisons of rural and urban differences in staging of breast cancer at diagnosis.

Results: Twenty-four studies were included in the systematic review and 21 studies had sufficient information for inclusion in the meta-analysis (N=879,660). Evidence indicated that patients residing in rural areas were more likely to be diagnosed with more advanced breast cancer. Using a random effects model, the results of the meta-analysis showed that rural breast cancer patients had 1.19 higher odds (95% confidence interval, 1.12-1.27) of late stage breast cancer compared with urban breast cancer patients.

Conclusions: Rural women were more likely than urban women to be diagnosed at a later stage. Preventive measures may need to target the rural population.
Keyword Breast neoplasms
Meta-analysis
Neoplasm staging
Rural health
Urban health
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online: 28 December 2013.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2014 Collection
School of Public Health Publications
 
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