A(2A) blockade enhances anti-metastatic immune responses

Beavis, Paul A., Milenkovski, Nicole, Stagg, John, Smyth, Mark J. and Darcy, Phillip K. (2013) A(2A) blockade enhances anti-metastatic immune responses. Oncoimmunology, 2 12: 1-3. doi:10.4161/onci.26705

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Author Beavis, Paul A.
Milenkovski, Nicole
Stagg, John
Smyth, Mark J.
Darcy, Phillip K.
Title A(2A) blockade enhances anti-metastatic immune responses
Formatted title
A2A blockade enhances anti-metastatic immune responses
Journal name Oncoimmunology   Check publisher's open access policy
ISSN 2162-4011
Publication date 2013-12-01
Year available 2013
Sub-type Article (original research)
DOI 10.4161/onci.26705
Open Access Status DOI
Volume 2
Issue 12
Start page 1
End page 3
Total pages 3
Place of publication Austin, TX, United States
Publisher Landes Bioscience
Language eng
Formatted abstract
The specific targeting of tumor-elicited immunosuppression is a promising strategy for the treatment of cancer. We have recently demonstrated that targeting the immunosuppressive pathway mediated by CD73-derived adenosine through the blockade of A2A/A2B adenosine receptors significantly reduced the metastatic potential of CD73+ breast carcinomas and melanomas via both immunological and non-immunological mechanisms.
Keyword Adenosine
Adenosine receptors
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published under Author's View. Article # e26705

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Medicine Publications
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