Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure

Lavie, Carl J., Alpert, Martin A., Arena, Ross, Mehra, Mandeep R., Milani, Richard V. and Ventura, Hector O. (2013) Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure. JACC: Heart Failure, 1 2: 93-102. doi:10.1016/j.jchf.2013.01.006


Author Lavie, Carl J.
Alpert, Martin A.
Arena, Ross
Mehra, Mandeep R.
Milani, Richard V.
Ventura, Hector O.
Title Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure
Journal name JACC: Heart Failure   Check publisher's open access policy
ISSN 2213-1779
2213-1787
Publication date 2013-01-01
Year available 2013
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.jchf.2013.01.006
Volume 1
Issue 2
Start page 93
End page 102
Total pages 10
Place of publication New York, NY United State
Publisher Elsevier Inc.
Language eng
Subject 2705 Cardiology and Cardiovascular Medicine
Abstract Obesity has reached epidemic proportions in the United States and worldwide. Considering the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function, and other risk factors for heart failure (HF), including hypertension and coronary heart disease, HF incidence and prevalence, not surprisingly, is markedly increased in obese patients. Nevertheless, as with most other cardiovascular diseases, numerous studies have documented an obesity paradox, in which overweight and obese patients, defined by body mass index, percent body fat, or central obesity, demonstrate a better prognosis compared with lean or underweight HF patients. This review will describe the data on obesity in the context of cardiopulmonary exercise testing in HF. Additionally, the implications of obesity on LV assist devices and heart transplantation are reviewed. Finally, despite the obesity paradox, we address the current state of weight reduction in HF.
Keyword Heart failure
Obesity
Obesity paradox
Overweight
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2014 Collection
School of Medicine Publications
 
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Created: Wed, 26 Feb 2014, 01:02:32 EST by Matthew Lamb on behalf of School of Medicine