The impact of obesity on risk factors and prevalence and prognosis of coronary heart disease-the obesity paradox

De Schutter, Alban, Lavie, Carl J. and Milani, Richard V. (2014) The impact of obesity on risk factors and prevalence and prognosis of coronary heart disease-the obesity paradox. Progress in Cardiovascular Diseases, 56 4: 401-408. doi:10.1016/j.pcad.2013.08.003


Author De Schutter, Alban
Lavie, Carl J.
Milani, Richard V.
Title The impact of obesity on risk factors and prevalence and prognosis of coronary heart disease-the obesity paradox
Journal name Progress in Cardiovascular Diseases   Check publisher's open access policy
ISSN 0033-0620
1873-1740
Publication date 2014-01-01
Sub-type Article (original research)
DOI 10.1016/j.pcad.2013.08.003
Open Access Status Not Open Access
Volume 56
Issue 4
Start page 401
End page 408
Total pages 8
Place of publication Maryland Heights, United States
Publisher W.B. Saunders Co.
Language eng
Abstract Obesity is associated with a host of cardiovascular risk factors and its prevalence is rising rapidly. Despite strong evidence that obesity predisposes to the development and progression of coronary heart disease (CHD), numerous studies have shown an inverse relationship between various measures of obesity (most commonly body mass index) and outcomes in established CHD. In this article we review the evidence surrounding the < obesity paradox. ≫ in the secondary care of CHD patients and the CHD presentations where a paradox has been found. Finally we discuss the impact of cardiorespiratory fitness and a number of mechanisms which may offer potential explanations for this puzzling phenomenon.
Keyword Coronary heart disease
Obesity
Obesity paradox
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
 
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