Enhancing expanded poly(tetrafluoroethylene) (ePTFE) for biomaterials applications

Cassady, A. Ian, Mohd Hidzir, Norsyahidah and Grøndahl, Lisbeth (2014) Enhancing expanded poly(tetrafluoroethylene) (ePTFE) for biomaterials applications. Journal of Applied Polymer Science, Early View 15: 1-14. doi:10.1002/app.40533

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Author Cassady, A. Ian
Mohd Hidzir, Norsyahidah
Grøndahl, Lisbeth
Title Enhancing expanded poly(tetrafluoroethylene) (ePTFE) for biomaterials applications
Journal name Journal of Applied Polymer Science   Check publisher's open access policy
ISSN 0021-8995
1097-4628
Publication date 2014-02-18
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/app.40533
Open Access Status Not yet assessed
Volume Early View
Issue 15
Start page 1
End page 14
Total pages 14
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Abstract Poly(tetrafluoroethylene) (PTFE), a fully fluorinated linear thermoplastic polymer, and in particular the porous form expanded PTFE (ePTFE) has found widespread use in biomaterials application due to its properties of high toughness, non-adhesiveness and hydrophobicity. While it performs ideally for many applications, some challenges have been identified for its use in small diameter vascular grafts and as a tissue space-filler for cosmetic reconstructions where the implant interfaces with bone. For these applications modification of the surface of ePTFE has been investigated as a means to enhance its performance. This review will focus on the applications listed above and will detail methods of evaluating the biological response, methods used to enhance the surface properties of ePTFE, and how the modified materials have performed in their intended applications. This review will focus on work published from 2004 onwards. (c) 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40533.
Formatted abstract
Poly(tetrafluoroethylene) (PTFE), a fully fluorinated linear thermoplastic polymer, and in particular the porous form expanded PTFE (ePTFE) has found widespread use in biomaterials application due to its properties of high toughness, non-adhesiveness and hydrophobicity. While it performs ideally for many applications, some challenges have been identified for its use in small diameter vascular grafts and as a tissue space-filler for cosmetic reconstructions where the implant interfaces with bone. For these applications modification of the surface of ePTFE has been investigated as a means to enhance its performance. This review will focus on the applications listed above and will detail methods of evaluating the biological response, methods used to enhance the surface properties of ePTFE, and how the modified materials have performed in their intended applications. This review will focus on work published from 2004 onwards.
Keyword Polymer Science
Polymer Science
POLYMER SCIENCE
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article first published online: 18 FEB 2014

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Chemistry and Molecular Biosciences
 
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Citation counts: TR Web of Science Citation Count  Cited 10 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 14 times in Scopus Article | Citations
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Created: Fri, 21 Feb 2014, 19:31:48 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences