Assessment of peripapillary retinal nerve fiber layer thickness using scanning laser polarimetry (GDx VCC) in normal Indian children

Khamar, Mayuri B, Vasavada, Vaishali, Shah, Sajani K, Trivedi, Rupal H and Thomas, Ravi (2013) Assessment of peripapillary retinal nerve fiber layer thickness using scanning laser polarimetry (GDx VCC) in normal Indian children. Indian Journal of Ophthalmology, 61 12: 728-733. doi:10.4103/0301-4738.121107


Author Khamar, Mayuri B
Vasavada, Vaishali
Shah, Sajani K
Trivedi, Rupal H
Thomas, Ravi
Title Assessment of peripapillary retinal nerve fiber layer thickness using scanning laser polarimetry (GDx VCC) in normal Indian children
Journal name Indian Journal of Ophthalmology   Check publisher's open access policy
ISSN 0301-4738
1998-3689
Publication date 2013-12-01
Sub-type Article (original research)
DOI 10.4103/0301-4738.121107
Open Access Status DOI
Volume 61
Issue 12
Start page 728
End page 733
Total pages 6
Place of publication Mumbai, India
Publisher Medknow Publications and Media
Language eng
Formatted abstract
Purpose: To obtain reference values of RNFL thickness in normal Indian children and to study the association of RNFL thickness with central corneal thickness(CCT) and axial length(AL).

Materials and Methods: 200 normal Indian children (mean age 8.6 ± 2.9 yrs) were examined on the GDxVCC. The inferior average (IA), superior average (SA), temporal-superior-nasal-inferior-temporal (TSNIT) average and nerve fiber index (NFI) values were recorded and compared between males and females as well as between the different age groups. The association of TSNIT average with AL and CCT was examined.

Results: Values for the RNFL parameters were-SA: 64.9 ± 9.7, IA: 63.8 ± 8.8, TSNIT average: 53.5 ± 7.7 and NFI 21.5 ± 10.8. Superior, inferior and TSNIT averages did not differ significantly between males and females (P = 0.25, P = 0.19, P = 0.06 respectively; Mann-Whitney U test). No significant differences were found in TSNIT average across age groups. There was a statistically significant positive correlation between CCT and TSNIT average (r = 0.25, r 2 = 0.06, P < 0.001). The correlation TSNIT average and AL(r = −0.12; r2 = 0.01) was not significant (P = 0.2).

Conclusion: Reference values for RNFL parameters reported for Indian children are similar those reported in adults. There is a small correlation between central corneal thickness and RNFL as reflected in average TSNIT.
Keyword Children
GDx variable corneal compensation
Indian
Normal
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
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