The neural correlates of risk propensity in males and females using resting-state fMRI

Zhou, Yuan, Li, Shu, Dunn, John, Li, Huandong, Qin, Wen, Zhu, Maohu, Rao, Li-Lin, Song, Ming, Yu, Chunshui and Jiang, Tianzi (2014) The neural correlates of risk propensity in males and females using resting-state fMRI. Frontiers in Behavioral Neuroscience, 8 JAN: . doi:10.3389/fnbeh.2014.00002

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Author Zhou, Yuan
Li, Shu
Dunn, John
Li, Huandong
Qin, Wen
Zhu, Maohu
Rao, Li-Lin
Song, Ming
Yu, Chunshui
Jiang, Tianzi
Title The neural correlates of risk propensity in males and females using resting-state fMRI
Journal name Frontiers in Behavioral Neuroscience   Check publisher's open access policy
ISSN 1662-5153
Publication date 2014-01-28
Year available 2014
Sub-type Article (original research)
DOI 10.3389/fnbeh.2014.00002
Open Access Status DOI
Volume 8
Issue JAN
Total pages 13
Place of publication Lausanne, Switzerland
Publisher Frontiers Research Foundation
Language eng
Abstract Men are more risk prone than women, but the underlying basis remains unclear. To investigate this question, we developed a trait-like measure of risk propensity which we correlated with resting-state functional connectivity to identify sex differences. Specifically, we used short- and long-range functional connectivity densities to identify associated brain regions and examined their functional connectivities in resting-state functional magnetic resonance imaging (fMRI) data collected from a large sample of healthy young volunteers. We found that men had a higher level of general risk propensity (GRP) than women. At the neural level, although they shared a common neural correlate of GRP in a network centered at the right inferior frontal gyrus, men and women differed in a network centered at the right secondary somatosensory cortex, which included the bilateral dorsal anterior/middle insular cortices and the dorsal anterior cingulate cortex. In addition, men and women differed in a local network centered at the left inferior orbitofrontal cortex. Most of the regions identified by this resting-state fMRI study have been previously implicated in risk processing when people make risky decisions. This study provides a new perspective on the brain-behavioral relationships in risky decision making and contributes to our understanding of sex differences in risk propensity.
Keyword Functional connectivity
Functional magnetic resonance imaging
Resting state
Risk propensity
Sex difference
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number 2.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2015 Collection
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 14 times in Scopus Article | Citations
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