Glass fibre-reinforced composite laced with chlorhexidine digluconate and yeast adhesion

Waltimo, T., Luo, G., Samaranayake, L. P. and Vallittu, P. K. (2004) Glass fibre-reinforced composite laced with chlorhexidine digluconate and yeast adhesion. Journal of Materials Science: Materials in Medicine, 15 2: 117-121. doi:10.1023/B:JMSM.0000011811.15602.3a

Author Waltimo, T.
Luo, G.
Samaranayake, L. P.
Vallittu, P. K.
Title Glass fibre-reinforced composite laced with chlorhexidine digluconate and yeast adhesion
Journal name Journal of Materials Science: Materials in Medicine   Check publisher's open access policy
ISSN 0957-4530
Publication date 2004-02-01
Sub-type Article (original research)
DOI 10.1023/B:JMSM.0000011811.15602.3a
Open Access Status Not yet assessed
Volume 15
Issue 2
Start page 117
End page 121
Total pages 5
Place of publication New York, NY, United States
Publisher Springer New York LLC
Language eng
Formatted abstract
The aim of this study was to lace dental glass fibre reinforced composite (FRC) prepreg with chlorhexidine digluconate and to examine the adherence of common oral fungal pathogen Candida albicans to FRC made of the prepreg. Four different test and control material groups each comprising 16 test specimens ((5.0 × 5.0 × 0.8) mm3) each were used as substrates for C. albicans adherence. A porous polymer pre-impregnated woven glass fibre prepreg was laced with solution of chlorhexidine gluconate and it was used with autopolymerized denture base polymer to fabricate FRC test specimens. Control group (Group 1) consisted of FRC test specimens stored in water. In Group 2, the test specimens were stored in 10% chlorhexidine digluconate solution for 24 h. Group 3 consisted of specimens fabricated using such fibre reinforcements which were pre-soaked in 20% chlorhexidine digluconate and dried before preparation with denture base resin, and followed by storage of the specimens in water. Group 4 was similar to Group 3 but instead of water storage the specimens were immersed in 10% chlorhexidine digluconate for 24 h. For the Candidal adhesion assay the test and control specimens were incubated in standardized suspensions of four different strains of C. albicans, rinsed and prepared for light-microscopy. The mean number of adherent cells in each group was counted microscopically and analysed statistically. There were significantly (P < 0.05) more adherent C. albicans cells found in Group 1 than in the other three groups which did not differ significantly from each other. The lowest numbers of adherent cells were found in Group 3. Pretreating the porous polymer pre-impregnated glass fibre reinforcement with chlorhexidine digluconate result in reduction in the number of adherent yeast cells on the surface FRC material.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
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Citation counts: TR Web of Science Citation Count  Cited 8 times in Thomson Reuters Web of Science Article | Citations
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