Biofilm lifestyle of Candida: a mini review

Seneviratne, C. J., Jin, L. and Samaranayake, L. P. (2008) Biofilm lifestyle of Candida: a mini review. Oral Diseases, 14 7: 582-590. doi:10.1111/j.1601-0825.2007.01424.x


Author Seneviratne, C. J.
Jin, L.
Samaranayake, L. P.
Title Biofilm lifestyle of Candida: a mini review
Journal name Oral Diseases   Check publisher's open access policy
ISSN 1354-523X
1601-0825
Publication date 2008-01-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1601-0825.2007.01424.x
Volume 14
Issue 7
Start page 582
End page 590
Total pages 9
Place of publication Malden, MA, United States
Publisher Wiley-Blackwell
Language eng
Subject 2733 Otorhinolaryngology
3500 Dentistry
Abstract Candida is the major fungal pathogen of humans causing a variety of afflictions ranging from superficial mucosal diseases to deep seated mycoses. Biofilm formation is a major virulence factor in the pathogenicity of Candida, and Candida biofilms are difficult to eradicate especially because of their very high antifungal resistance. Consequently, research into the pathogenicity of Candida has focused on the prevention and management of biofilm development, their architecture, and antifungal resistance. Although studies have shed some light, molecular mechanisms that govern biofilm formation and pathogenicity still await full clarification. This review outlines the key features of what is currently known of Candida biofilm development, regulation and antifungal resistance and, their proteomics.
Keyword Antifungal resistance
Biofilm
Candida
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Dentistry Publications
 
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