Oral mucosal fungal infections

Samaranayake, Lakshman P., Leung, W. Keung and Jin, Lijian (2009) Oral mucosal fungal infections. Periodontology 2000, 49 1: 39-59. doi:10.1111/j.1600-0757.2008.00291.x

Author Samaranayake, Lakshman P.
Leung, W. Keung
Jin, Lijian
Title Oral mucosal fungal infections
Journal name Periodontology 2000   Check publisher's open access policy
ISSN 0906-6713
ISBN 978-1-119-94143-9
Publication date 2009-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1111/j.1600-0757.2008.00291.x
Open Access Status DOI
Volume 49
Issue 1
Start page 39
End page 59
Total pages 21
Place of publication Malden, MA, United States
Publisher Wiley-Blackwell
Language eng
Subject 3506 Periodontics
Abstract This review has provided an overview of variants of oral mucosal candidiasis and current therapeutic techniques followed by an outline of the rare oral mycoses and their management. The advent of the HIV infection and the increasing prevalence of compromised individuals in the community as a consequence of surgical and medical advances have resulted in a resurgence of opportunistic infections, including oral candidiasis and other rare mycoses that were once considered exotic. It is now recognized that oral candidiasis may present in many clinical guises, including the classic white lesion of thrush as well in as nondescript, red mucosal lesions that may confound the unwary clinician. Other mycotic diseases, such as aspergillosis, cryptococcosis, histoplasmosis and mucormycosis, may manifest intra-orally, both as primary lesions and as secondary manifestations of systemic disease. Periodontal manifestations of mycotic diseases are rare. If at all, such lesions may present as erythematous areas as in linear gingival erythema and rarely as ulcerations in exotic mycoses. Most of the oral mycoses respond well to either topical or systemic therapy with the polyenes or azoles. In general, the management of oral fungal infections has been revolutionized by the triazole group of drugs, fluconazole and itraconazole, although recent reports indicate an alarming increase of resistant organisms, in particular to fluconazole.
Keyword Pharmacology & Pharmacy
Pharmacology & Pharmacy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
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Citation counts: TR Web of Science Citation Count  Cited 85 times in Thomson Reuters Web of Science Article | Citations
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