Oral health promotion interventions on oral yeast in hospitalised and medically compromised patients: A systematic review

Lam, Otto L. T., Bandara, H. M. H. N., Samaranayake, Lakshman P., Mcgrath, Colman and Li, Leonard S. W. (2012) Oral health promotion interventions on oral yeast in hospitalised and medically compromised patients: A systematic review. Mycoses, 55 2: 123-142. doi:10.1111/j.1439-0507.2011.02062.x


Author Lam, Otto L. T.
Bandara, H. M. H. N.
Samaranayake, Lakshman P.
Mcgrath, Colman
Li, Leonard S. W.
Title Oral health promotion interventions on oral yeast in hospitalised and medically compromised patients: A systematic review
Journal name Mycoses   Check publisher's open access policy
ISSN 0933-7407
1439-0507
Publication date 2012-01-01
Year available 2012
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1439-0507.2011.02062.x
Volume 55
Issue 2
Start page 123
End page 142
Total pages 20
Place of publication Berlin, Germany
Publisher Wiley-Blackwell Verlag GmbH
Language eng
Subject 2708 Dermatology
2725 Infectious Diseases
Abstract Yeast are major aetiological agents of localised oral mucosal lesions, and are also leading causes of nosocomial bloodstream infections. The purpose of this systematic review was to examine the effectiveness of oral health promotion interventions on the prevalence and incidence of these opportunistic oral pathogens in hospitalised and medically compromised patients. The PubMed, ISI Web of Science and Cochrane Library databases were searched for clinical trials assessing the effect of oral health promotion interventions on oral yeast. Chlorhexidine delivered in a variety of oral hygiene products appeared to have some effect on oral yeast, although some studies found equivocal effects. Although a wide array of other compounds have also been investigated, their clinical effectiveness remains to be substantiated. Likewise, the utility of mechanical oral hygiene interventions and other oral health promotion measures such as topical application of salivary substitute, remains unsettled. Although many chemical agents contained in oral hygiene products have proven in vitro activity against oral yeast, their clinical effectiveness and potential role as adjuncts or alternative therapies to conventional treatment remains to be confirmed by further high-quality randomised controlled trials. This is pertinent, given the recent emergence of yeast resistance to conventional antifungal agents.
Keyword Health promotion
Oral
Yeast
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Dentistry Publications
 
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