Neural regulation of inflammation in the airways and lungs

McGovern, Alice E. and Mazzone, Stuart B. (2013) Neural regulation of inflammation in the airways and lungs. Autonomic Neuroscience: Basic and Clinical, 182 95-101. doi:10.1016/j.autneu.2013.12.008

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Author McGovern, Alice E.
Mazzone, Stuart B.
Title Neural regulation of inflammation in the airways and lungs
Journal name Autonomic Neuroscience: Basic and Clinical   Check publisher's open access policy
ISSN 1566-0702
Publication date 2013-12-23
Year available 2013
Sub-type Article (original research)
DOI 10.1016/j.autneu.2013.12.008
Volume 182
Start page 95
End page 101
Total pages 7
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Formatted abstract
Many pulmonary diseases are characterized by inflammatory pathologies which in turn are responsible for obstruction, mucus hypersecretion, dyspnea, cough and other clinical symptoms of lung disease. Understanding processes that regulate inflammation will therefore provide insights into mechanisms that contribute to pulmonary dysfunction. The airways and lungs are densely innervated by autonomic and sensory nerves which might regulate aspects of pulmonary inflammation. In this review we provide a critical appraisal of the available literature on the topic of neuro-immune interactions in the airways and ask the question ‘how strong is the evidence that pulmonary nerves regulate inflammation?’
Keyword Neuro-immune
Immune synapse
Airway reflexes
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 23 December 2013

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Biomedical Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 8 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 8 times in Scopus Article | Citations
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Created: Mon, 03 Feb 2014, 17:58:45 EST by Dr Stuart Mazzone on behalf of School of Biomedical Sciences