Psychotropic medication use in adolescents with intellectual disability living in the community

Doan, Tan, Ware, Robert, Mcpherson, Lyn, van Dooren, Kate, Bain, Christopher, Carrington, Suzanne, Einfeld, Stewart, Tonge, Bruce and Lennox, Nicholas (2014) Psychotropic medication use in adolescents with intellectual disability living in the community. Pharmacoepidemiology and Drug Safety, 23 1: 69-76. doi:10.1002/pds.3484

Author Doan, Tan
Ware, Robert
Mcpherson, Lyn
van Dooren, Kate
Bain, Christopher
Carrington, Suzanne
Einfeld, Stewart
Tonge, Bruce
Lennox, Nicholas
Title Psychotropic medication use in adolescents with intellectual disability living in the community
Journal name Pharmacoepidemiology and Drug Safety   Check publisher's open access policy
ISSN 1053-8569
Publication date 2014-01-01
Year available 2013
Sub-type Article (original research)
DOI 10.1002/pds.3484
Open Access Status Not yet assessed
Volume 23
Issue 1
Start page 69
End page 76
Total pages 8
Place of publication Chichester, West Sussex, United Kingdom
Publisher John Wiley and Sons Ltd
Language eng
Subject 2736 Pharmacology (medical)
2713 Epidemiology
Abstract Purpose: Information on the use of psychotropic medications in adolescents with intellectual disability is scant. Such information can guide interventions to improve psychotropic medication use in this population. We investigated the prevalence of, and factors associated with, psychotropic medication use in adolescents with intellectual disability in Australia who live in the community. Methods: Cross-sectional data were obtained from adolescents with intellectual disability living in the community in South East Queensland, Australia, between February 2007 and September 2010. Self-reported information on medication use was extracted from a health screening tool. Demographic and medical data were collected through parent/caregiver surveys. Medications were classified according to the Anatomical Therapeutic Chemical classification system. Psychopathology was assessed using the Developmental Behaviour Checklist Short Form. Logistic regression analysis was used to assess the association of demographic and medical characteristics with psychotropic medication use. Results: There were 176 participants (median age=16years, range=11-19years; 55% male). Psychotropics were used by 20% of participants. Psychostimulants were the commonest psychotropic class, used by 9% of participants. Multipsychotropic prescribing was not common with only seven participants using more than one psychotropic agent. After adjusting for potentially confounding variables, use of psychotropic medications was significantly associated with male gender (adjusted odds ratio=3.6; 95% confidence interval=1.3-9.5) and having major behaviour problems (3.1; 1.1-8.9). Conclusions: Adolescents with intellectual disability use a wide range of psychotropic medications. Being male and having major behaviour problems are associated with the use of psychotropic medications. Research examining the rationale for psychotropic prescribing in this population is needed.
Keyword Adolescent
Intellectual disability
Psychotropic medication
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID 401647
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
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