Occurrence of closely spaced genes in the nuclear genome of the agarophyte Gracilaria gracilis

Lluisma A.O. and Ragan M.A. (1999) Occurrence of closely spaced genes in the nuclear genome of the agarophyte Gracilaria gracilis. Journal of Applied Phycology, 11 1: 99-104. doi:10.1023/A:1008008906649

Author Lluisma A.O.
Ragan M.A.
Title Occurrence of closely spaced genes in the nuclear genome of the agarophyte Gracilaria gracilis
Journal name Journal of Applied Phycology   Check publisher's open access policy
ISSN 0921-8971
Publication date 1999-01-01
Year available 1999
Sub-type Article (original research)
DOI 10.1023/A:1008008906649
Open Access Status Not yet assessed
Volume 11
Issue 1
Start page 99
End page 104
Total pages 6
Place of publication DORDRECHT
Language eng
Subject 1104 Complementary and Alternative Medicine
1305 Biotechnology
Abstract Little is known about the structure and organisation of nuclear genomes in red algae. In particular, it is not known whether genes are densely or loosely packed, whether gene order is conserved, whether their genes tend to occur in one or multiple copies and whether their nuclear genes tend to be compact or interrupted by numerous introns. Sequencing of cloned genomic DNA from Gracilaria gracilis has begun to provide provisional answers to some of these questions. Four pairs of closely spaced genes have been found in G. gracilis upon sequencing genomic clones that contain genes for UDPglucose pyrophosphorylase, galactose-1-phosphate uridylyltransferase, the beta subunit of tryptophan synthetase, and methionine sulphoxide reductase (a fifth pair of closely spaced genes, encoding polyubiquitin and aconitase, was reported earlier). An open reading frame with significant similarity to another known gene occurs close (< 1.7 kbp) to each of these genes. In two pairs the intergenic region is less than 400 bp in length, and for these the location of the putative polyadenylation signals indicates that the gene transcripts, encoded on opposite strands, have overlapping (hence complementary) 3' regions. These somewhat unexpected findings begin to establish a basis for genome-level characterisation of red algae.
Keyword Genome organisation
Genome structure
Red algae
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
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