An archaebacterial homolog of pelota, a meiotic cell division protein in eukaryotes

Ragan, MA, Logsdon, JM, Sensen, CW, Charlebois, RL and Doolittle, WF (1996) An archaebacterial homolog of pelota, a meiotic cell division protein in eukaryotes. Fems Microbiology Letters, 144 2-3: 151-155. doi:10.1111/j.1574-6968.1996.tb08522.x


Author Ragan, MA
Logsdon, JM
Sensen, CW
Charlebois, RL
Doolittle, WF
Title An archaebacterial homolog of pelota, a meiotic cell division protein in eukaryotes
Journal name Fems Microbiology Letters   Check publisher's open access policy
ISSN 0378-1097
Publication date 1996-11-01
Year available 1996
Sub-type Article (original research)
DOI 10.1111/j.1574-6968.1996.tb08522.x
Open Access Status Not yet assessed
Volume 144
Issue 2-3
Start page 151
End page 155
Total pages 5
Place of publication OXFORD
Publisher OXFORD UNIV PRESS
Language eng
Abstract An open reading frame (pelA) specifying a homolog of pelota and DOM34, proteins required for meiotic cell division in Drosophila melanogaster and Saccharomyces cerevisiae, respectively, has been cloned, sequenced and identified from the archaebacterium Sulfolobus solfataricus. The S. solfataricus PelA protein is about 20% identical with pelota, DOM34 and the hypothetical protein R74.6 of Caenorhabditis elegans. The presence of a pelota homolog in archaebacteria implies that the meiotic functions of the eukaryotic protein were co-opted from, or added to, other functions existing before the emergence of eukaryotes. The nuclear localization signal and negatively charged carboxy-terminus characteristic of eukaryotic pelota-like proteins are absent from the S. solfataricus homolog, and hence may be indicative of the acquired eukaryotic function(s).
Keyword (Sulfolobus solfataricus)
Archaea
Archaebacterium
meiosis
pelota
Dom34
Nucleotide-Sequence
Transcription Factor
Secondary Structure
Globular-Proteins
Chromosome-Xiv
Archaea
Gene
Sulfolobus
Alignment
Accuracy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 22 Jan 2014, 22:31:20 EST by System User