MRI phase contrast velocity and flow errors in turbulent stenotic jets

O'Brien, Kieran R., Cowan, Brett R., Jain, Manali, Stewart , Ralph A. H., Kerr, Andrew J. and Young, Alistair A. (2008) MRI phase contrast velocity and flow errors in turbulent stenotic jets. Journal of Magnetic Resonance Imaging, 28 1: 210-218. doi:10.1002/jmri.21395


Author O'Brien, Kieran R.
Cowan, Brett R.
Jain, Manali
Stewart , Ralph A. H.
Kerr, Andrew J.
Young, Alistair A.
Title MRI phase contrast velocity and flow errors in turbulent stenotic jets
Journal name Journal of Magnetic Resonance Imaging   Check publisher's open access policy
ISSN 1053-1807
1522-2586
Publication date 2008-07-01
Sub-type Article (original research)
DOI 10.1002/jmri.21395
Open Access Status Not Open Access
Volume 28
Issue 1
Start page 210
End page 218
Total pages 9
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Purpose: To clarify the use of MRI phase contrast (PC), as an alternative to Doppler echocardiography, when measuring high-velocity turbulent jets associated with stenotic valvular disease.

Materials and Methods: In vivo PC aortic stroke volume (SV) was compared with ventricular SV in 31 patients with moderate to severe aortic stenosis (AS). Two in vitro pipe experiments were conducted to evaluate errors in steady stenotic and nonstenotic turbulent flows.

Results: The average in vivo error in SV was −24% in the left-ventricular (LV) outflow tract (LVOT) and −41% in the aortic root. Errors were most prominent in patients with the highest Doppler peak velocities. In vitro nonstenotic flow experiments showed accurate flow measurement with an average error of 1.8%. Significant errors were found in the in vitro stenotic flow, which reduced with shorter echo times (TE): average error −166/−67/−25/−13/−8.8% for TEs of 4.8/4.0/3.3/2.2/2.0 msec. In both the in vivo and in vitro stenotic experiments the errors were associated with signal loss in the flow-compensated magnitude image.

Conclusion: Signal loss is associated with flow errors in stenotic jets. Current clinically available PC pulse sequences with TE >2 msec may not accurately quantify flow for severe lesions.
Keyword Aortic stenosis
Phase contrast
Turbulence
Jet
Errors
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
 
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Created: Wed, 15 Jan 2014, 23:05:17 EST by Kieran O'brien on behalf of Centre for Advanced Imaging