Neural changes after phonological treatment for anomia: an fMRI study

Rochon, Elizabeth, Leonard, Carol, Burianova, Hana, Laird, Laura, Soros, Peter, Graham, Simon and Grady, Cheryl (2010) Neural changes after phonological treatment for anomia: an fMRI study. Brain and Language, 114 3: 164-179. doi:10.1016/j.bandl.2010.05.005


Author Rochon, Elizabeth
Leonard, Carol
Burianova, Hana
Laird, Laura
Soros, Peter
Graham, Simon
Grady, Cheryl
Title Neural changes after phonological treatment for anomia: an fMRI study
Journal name Brain and Language   Check publisher's open access policy
ISSN 0093-934X
1090-2155
Publication date 2010-01-01
Year available 2010
Sub-type Article (original research)
DOI 10.1016/j.bandl.2010.05.005
Open Access Status Not Open Access
Volume 114
Issue 3
Start page 164
End page 179
Total pages 16
Place of publication Maryland Heights, MO, United States
Publisher Academic Press
Language eng
Abstract Functional magnetic resonance imaging (fMRI) was used to investigate the neural processing characteristics associated with word retrieval abilities after a phonologically-based treatment for anomia in two stroke patients with aphasia. Neural activity associated with a phonological and a semantic task was compared before and after treatment with fMRI. In addition to the two patients who received treatment, two patients with aphasia who did not receive treatment and 10 healthy controls were also scanned twice. In the two patients who received treatment, both of whose naming improved after treatment, results showed that activation patterns changed after treatment on the semantic task in areas that would have been expected (e.g., left hemisphere frontal and temporal areas). For one control patient, there were no significant changes in brain activation at the second scan; a second control patient showed changes in brain activation at the second scan, on the semantic task, however, these changes were not accompanied with improved performance in naming. In addition, there appeared to be bilateral, or even more right than left hemisphere brain areas activated in this patient than in the treated patients. The healthy control group showed no changes in activation at the second scan. These findings are discussed with reference to the literature on the neural underpinnings of recovery after treatment for anomia in aphasia.
Keyword Anomia
Aphasia
FMRI
Neuroimaging
Treatment
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID s 5379
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
 
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