Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) study

Maple-Brown, Louise J., Brown, Alex, Lee, I.-Lynn, Connors, Christine, Oats, Jeremy, McIntyre, Harold D., Whitbread, Cherie, Moore, Elizabeth, Longmore, Danielle, Dent, Glynis, Corpus, Sumaria, Kirkwood, Marie, Svenson, Stacey, van Dokkum, Paula, Chitturi, Sridhar, Thomas, Sujatha, Eades, Sandra, Stone, Monique, Harris, Mark, Inglis, Chrissie, Dempsey, Karen, Dowden, Michelle, Lynch, Michael, Boyle, Jacqueline, Sayers, Sue, Shaw, Jonathan, Zimmet, Paul and O'Dea, Kerin (2013) Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) study. BMC Pregnancy and Childbirth, 13 6: 534-540. doi:10.1186/1471-2393-13-221

Author Maple-Brown, Louise J.
Brown, Alex
Lee, I.-Lynn
Connors, Christine
Oats, Jeremy
McIntyre, Harold D.
Whitbread, Cherie
Moore, Elizabeth
Longmore, Danielle
Dent, Glynis
Corpus, Sumaria
Kirkwood, Marie
Svenson, Stacey
van Dokkum, Paula
Chitturi, Sridhar
Thomas, Sujatha
Eades, Sandra
Stone, Monique
Harris, Mark
Inglis, Chrissie
Dempsey, Karen
Dowden, Michelle
Lynch, Michael
Boyle, Jacqueline
Sayers, Sue
Shaw, Jonathan
Zimmet, Paul
O'Dea, Kerin
Title Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) study
Journal name BMC Pregnancy and Childbirth   Check publisher's open access policy
ISSN 1471-2393
Publication date 2013-12-01
Year available 2014
Sub-type Article (original research)
DOI 10.1186/1471-2393-13-221
Open Access Status DOI
Volume 13
Issue 6
Start page 534
End page 540
Total pages 8
Place of publication London, United Kingdom
Publisher BioMed Central Ltd
Language eng
Subject 2729 Obstetrics and Gynaecology
Abstract Background: Diabetes in pregnancy carries an increased risk of adverse pregnancy outcomes for both the mother and foetus, but it also provides an excellent early opportunity for intervention in the life course for both mother and baby. In the context of the escalating epidemic of chronic diseases among Indigenous Australians, it is vital that this risk is reduced as early as possible in the life course of the individual. The aims of the PANDORA Study are to: (i) accurately assess rates of diabetes in pregnancy in the Northern Territory (NT) of Australia, where 38% of babies are born to Indigenous mothers; (ii) assess demographic, clinical, biochemical, anthropometric, socioeconomic and early life development factors that may contribute to key maternal and neonatal birth outcomes associated with diabetes in pregnancy; and (iii) monitor relevant post-partum clinical outcomes for both the mothers and their babies.Methods/Design: Eligible participants are all NT women with diabetes in pregnancy aged 16 years and over. Information collected includes: standard antenatal clinical information, diagnosis and management of diabetes in pregnancy, socio-economic status, standard clinical birth information (delivery, gestational age, birth weight, adverse antenatal and birth outcomes). Cord blood is collected at the time of delivery and detailed neonatal anthropometric measurements performed within 72 hours of birth. Information will also be collected regarding maternal post-partum glucose tolerance and cardio-metabolic risk factor status, breastfeeding and growth of the baby up to 2 years post-partum in the first instance.Discussion: This study will accurately document rates and outcomes of diabetes in pregnancy in the NT of Australia, including the high-risk Indigenous Australian population. The results of this study should contribute to policy and clinical guidelines with the goal of reducing the future risk of obesity and diabetes in both mothers and their offspring.
Keyword Aboriginal
Antenatal care
Birth weight
Diabetes in pregnancy
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID 1032116
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Mater Research Institute-UQ (MRI-UQ)
Official 2014 Collection
School of Public Health Publications
School of Medicine Publications
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