A report on the Genetics of Complex Diseases meeting of the British Atherosclerosis Society, Cambridge, UK, 17-18 September 2009

Holmes, Michael V., Shah, Sonia H., Angelakopoulou, Aspasia, Khan, Tauseef, Swerdlow, Daniel, Kuchenbaecker, Karoline, Sofat, Reecha and Shah, Tina (2010) A report on the Genetics of Complex Diseases meeting of the British Atherosclerosis Society, Cambridge, UK, 17-18 September 2009. Atherosclerosis, 208 2: 599-602. doi:10.1016/j.atherosclerosis.2009.11.034


Author Holmes, Michael V.
Shah, Sonia H.
Angelakopoulou, Aspasia
Khan, Tauseef
Swerdlow, Daniel
Kuchenbaecker, Karoline
Sofat, Reecha
Shah, Tina
Title A report on the Genetics of Complex Diseases meeting of the British Atherosclerosis Society, Cambridge, UK, 17-18 September 2009
Journal name Atherosclerosis   Check publisher's open access policy
ISSN 0021-9150
1879-1484
Publication date 2010-02-01
Sub-type Review of book, film, TV, video, software, performance, music etc
DOI 10.1016/j.atherosclerosis.2009.11.034
Open Access Status Not Open Access
Volume 208
Issue 2
Start page 599
End page 602
Total pages 4
Place of publication E. Park, Shannon, Co. Clare, Ireland
Publisher Elsevier Ireland
Language eng
Subject 2705 Cardiology and Cardiovascular Medicine
Formatted abstract
The study of complex disease genetics is at a critical turning point. Development of high-throughput technology has enabled a change in the investigational approach from traditional candidate gene studies to hypothesis-free genome-wide association studies (GWAS). These experiments have generated an abundance of data, novel analytic methods, some answers but also many questions. The aim of this year's Autumn meeting of the British Atherosclerosis Society was to update members on research in complex disease genetics. This common platform has brought together a number of scientific disciplines including genetics, epidemiology, bioinformatics, statistics and medicine, all of which were reflected in the diverse backgrounds of speakers and delegates at this meeting.

Two principal themes emerged from this meeting and are summarised here. Firstly the success of GWAS in discovery of novel disease loci with emerging novel analytical methodologies to interpret this abundance of data (and how to overcome their limitations) and secondly, the translational application of the information gathered so far from GWAS, and what we can expect in the future...
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Review of book, film, TV, video, software, performance, music etc
Collection: Queensland Brain Institute Publications
 
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