Lateral genetic transfer and cellular networks

Skippington, Elizabeth and Ragan, Mark A. (2013). Lateral genetic transfer and cellular networks. In Uri Gophna (Ed.), Lateral gene transfer in evolution (pp. 123-135) New York, United States: Springer. doi:10.1007/978-1-4614-7780-8_6

Author Skippington, Elizabeth
Ragan, Mark A.
Title of chapter Lateral genetic transfer and cellular networks
Title of book Lateral gene transfer in evolution
Place of Publication New York, United States
Publisher Springer
Publication Year 2013
Sub-type Research book chapter (original research)
DOI 10.1007/978-1-4614-7780-8_6
Open Access Status Not yet assessed
ISBN 9781461477792
Editor Uri Gophna
Chapter number 6
Start page 123
End page 135
Total pages 13
Total chapters 15
Language eng
Subjects 2700 Medicine
1300 Biochemistry, Genetics and Molecular Biology
Abstract/Summary Each step in the temporal process of lateral genetic transfer (LGT) presents barriers and biases that, together with contingent processes in the environment, determine the success of transfer events. Appropriate interaction with existing host systems, together with regulated expression of gene products, are particularly important for the long-term establishment of transferred DNA. Large datasets of biological interactions can be abstracted to construct graphical abstractions of cellular networks. Phyletic distributions and other metadata can then be mapped onto these networks to examine hypotheses of network properties that contribute to successful LGT. Here we examine the organising principles that govern the integration of laterally transferred DNA with existing host cellular networks.
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ

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Created: Tue, 17 Dec 2013, 01:52:31 EST by Susan Allen on behalf of Institute for Molecular Bioscience