Screening for lung cancer with low-dose computed tomography: a review of current status

Marshall, Henry M., Bowman, Rayleen V., Yang, Ian A., Fong, Kwun M. and Berg, Christine D. (2013) Screening for lung cancer with low-dose computed tomography: a review of current status. Journal of Thoracic Disease, 5 SUPPL.5: S524-S539. doi:10.3978/j.issn.2072-1439.2013.09.06

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Author Marshall, Henry M.
Bowman, Rayleen V.
Yang, Ian A.
Fong, Kwun M.
Berg, Christine D.
Title Screening for lung cancer with low-dose computed tomography: a review of current status
Journal name Journal of Thoracic Disease   Check publisher's open access policy
ISSN 2072-1439
2077-6624
Publication date 2013-10-01
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.3978/j.issn.2072-1439.2013.09.06
Open Access Status Not yet assessed
Volume 5
Issue SUPPL.5
Start page S524
End page S539
Total pages 16
Place of publication Hong Kong, Hong Kong
Publisher Pioneer Bioscience Publishing Company
Language eng
Abstract Screening using low-dose computed tomography (CT) represents an exciting new development in the struggle to improve outcomes for people with lung cancer. Randomised controlled evidence demonstrating a 20% relative lung cancer mortality benefit has led to endorsement of screening by several expert bodies in the US and funding by healthcare providers. Despite this pivotal result, many questions remain regarding technical and logistical aspects of screening, cost-effectiveness and generalizability to other settings. This review discusses the rationale behind screening, the results of on-going trials, potential harms of screening and current knowledge gaps.
Keyword Lung neoplasms/mortality
mass screening tomography
helical computed
early detection of cancer/methods
Small Pulmonary Nodules
Maximum Intensity Projection
Term-Follow-Up
Trial Nelson
Fleischner-Society
Cost-Effectiveness
Risk Prediction
Spiral Ct
Chest Ct
Randomized Feasibility
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2014 Collection
School of Medicine Publications
 
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