Changes in temperature affect the risk of abdominal aortic aneurysm rupture

Brightwell, Robert E., Choong, Andrew M. T. L., Barnett, Adrian G. and Walker, Philip J. (2013) Changes in temperature affect the risk of abdominal aortic aneurysm rupture. ANZ Journal of Surgery, Early View 1-6. doi:10.1111/ans.12446

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Author Brightwell, Robert E.
Choong, Andrew M. T. L.
Barnett, Adrian G.
Walker, Philip J.
Title Changes in temperature affect the risk of abdominal aortic aneurysm rupture
Journal name ANZ Journal of Surgery   Check publisher's open access policy
ISSN 1445-1433
Publication date 2013-11-26
Year available 2013
Sub-type Article (original research)
DOI 10.1111/ans.12446
Open Access Status
Volume Early View
Start page 1
End page 6
Total pages 6
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Language eng
Formatted abstract
Background There is a well-established link between exposure to hot and cold temperatures and an increased risk of cardiovascular hospitalization or death. There is also contrasting evidence of a seasonal increase in aortic ruptures related to atmospheric pressure, but an association with environmental temperature has never been formally modelled.

Methods Using a prospective database, we identified 295 patients who were operated in a single centre for ruptured abdominal aortic aneurysm in south-east Queensland between 1990 and 2010. We matched patients to their nearest weather station to estimate their exposure to temperature and air pressure in the days leading up to their rupture. We used the case–crossover method to estimate the risks of temperature, which we allowed to be non-linear (increased risks at high and low temperatures) and delayed by up to 25 days.

Results There was an immediate increase in risk after exposure to cold, and a delayed risk after exposure to heat. An increased risk after exposure to high pressures disappeared after adjusting for temperature. At a mean temperature of 19°C (66°F), the odds ratio for rupture was 1.73 (95% confidence interval: 1.09, 2.76) compared with the reference temperature of 24°C.

Conclusion This is the first study to demonstrate an association between temperature and risk of aortic aneurysm rupture in the Southern Hemisphere. The physiological changes caused by thermoregulation may be a trigger for those people with a fragile aneurysm.
Keyword Abdominal aortic aneurysm
Epidemiology, temperature
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Authors prepress title: "Changes in Environmental Temperature affect the risk of Abdominal Aortic Aneurysm Rupture". Article first published online: 26 NOV 2013

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2014 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 11 Dec 2013, 21:39:33 EST by Roheen Gill on behalf of Surgery - Royal Brisbane and Women's Hospital